83004-13-1Relevant articles and documents
IRAK4 INHIBITING AGENTS
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Page/Page column 52, (2017/09/24)
Provided are compounds of Formula I, or pharmaceutically acceptable salts thereof, and methods for their use and production. Formula (I) The compounds are IRAK-4 inhibitors useful for treating an inflammatory disease, an autoimmune disease, cancer, a cardiovascular disease, a disease of the central nervous system, a disease of the skin, an ophthalmic disease and condition, and a bone disease.
Rare-earth-catalyzed C-H bond addition of pyridines to olefins
Guan, Bing-Tao,Hou, Zhaomin
supporting information; experimental part, p. 18086 - 18089 (2012/01/03)
An efficient and general protocol for the ortho-alkylation of pyridines via C-H addition to olefins has been developed, using cationic half-sandwich rare-earth catalysts, which provides an atom-economical method for the synthesis of alkylated pyridine der
3-INDAZOLYL-4-PYRIDYLISOTHIAZOLES
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Page/Page column 9, (2009/10/18)
The present invention provides 3-indazoyl-4-pyridylisothiazoles or a pharmaceutically acceptable salt thereof, pharmaceutical compositions thereof, and methods of using the same, as well as processes for preparing the same, and intermediates thereof.