83015-26-3 Usage
Description
(R)-Tomoxetine, also known as (R)-Tomoxetine hydrochloride, is a secondary amino compound characterized by its methyl and 3-(2-methylphenoxy)-3-phenylpropan-1-yl substituents. It is a chiral molecule with a specific stereochemistry that plays a crucial role in its biological activity. As an enantiomer of Tomoxetine, (R)-Tomoxetine exhibits unique pharmacological properties and is considered a promising candidate for the development of novel therapeutic agents.
Uses
Used in Pharmaceutical Industry:
(R)-Tomoxetine is used as a compound active at a novel site on receptor-operated calcium channels for the treatment of neurological disorders and diseases. Its unique mechanism of action allows it to modulate calcium channel activity, which can have therapeutic benefits in various neurological conditions.
The specific stereochemistry of (R)-Tomoxetine contributes to its selectivity and potency, making it a valuable asset in the development of targeted therapies for neurological disorders. Its potential applications include the treatment of conditions such as Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders, as well as various forms of chronic pain and epilepsy.
Furthermore, the chiral nature of (R)-Tomoxetine may also provide insights into the role of stereochemistry in drug design and development, leading to the discovery of new and more effective therapeutic agents. As research continues, (R)-Tomoxetine may pave the way for innovative treatments and improved patient outcomes in the field of neurology.
Check Digit Verification of cas no
The CAS Registry Mumber 83015-26-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,0,1 and 5 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 83015-26:
(7*8)+(6*3)+(5*0)+(4*1)+(3*5)+(2*2)+(1*6)=103
103 % 10 = 3
So 83015-26-3 is a valid CAS Registry Number.
InChI:InChI=1/C17H21NO/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15/h3-11,17-18H,12-13H2,1-2H3/t17-/m1/s1
83015-26-3Relevant articles and documents
Preparation method of cefamoxetine hydrochloride
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Paragraph 0008; 0018-0019; 0022; 0025; 0028, (2021/10/27)
The invention discloses a preparation method of tamoxidectin hydrochloride, belongs to the technical field of drug synthesis, and uses 3 - chlorine -1 - phenylpropanone as a raw material to undergo a reduction reaction. The synthesis route has the advantages of few reaction steps, mild reaction conditions,3 - simple 2 - operation, cheap -3 - and easily available raw materials, and low production cost 3 - and -1 - R-chloro - N - phenylpropanone is used as a raw material.
Preparation method of atomoxetine hydrochloride
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, (2020/06/09)
The invention belongs to the technical field of medicines, and particularly relates to a preparation method of atomoxetine hydrochloride serving as a medicine for treating attention deficit hyperactivity. According to the invention, commercially available (E)-N-methyl-3-phenyl-2-propylene-1-amine is adopted as a starting material, and addition, substitution and salification are carried out so as to prepare atomoxetine hydrochloride. The preparation method provided by the invention is simple in preparation process, simple and convenient to operate, relatively high in yield and suitable for industrial production, and can provide sufficient bulk drugs for research and development of medicines.
Preparation method of atomoxetine
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Paragraph 0003; 0012; 0013, (2020/06/05)
The invention belongs to the technical field of medicines, and particularly relates to a preparation method of atomoxetine hydrochloride serving as a medicine for treating attention deficit hyperactivity. Commercially available 3-(methylamino)-1-phenylacetone is adopted as a starting material, and undergoes asymmetric reduction, substitution and other reactions to prepare the atomoxetine. The invention mainly aims to prepare the atomoxetine by an asymmetric synthesis method and expand a preparation method of the atomoxetine hydrochloride.