83016-75-5

Basic information

• Product Name: 1-(PhenylMethoxy)-3-(2-propen-1-yloxy)-2-propanol
• Synonyms: 1-(PhenylMethoxy)-3-(2-propen-1-yloxy)-2-propanol
• CAS NO: 83016-75-5
• Molecular Formula: C₁₃H₁₈O₃
• Molecular Weight: 222.28022
• Product Categories: Aromatics;Heterocycles
• Mol File: 83016-75-5.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Solubility: Dichloromethane
• CAS DataBase Reference: 1-(PhenylMethoxy)-3-(2-propen-1-yloxy)-2-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(PhenylMethoxy)-3-(2-propen-1-yloxy)-2-propanol(83016-75-5)
• EPA Substance Registry System: 1-(PhenylMethoxy)-3-(2-propen-1-yloxy)-2-propanol(83016-75-5)

Safety Data

• Hazardous Substances Data: 83016-75-5(Hazardous Substances Data)

Usage

Chemical Properties

Colorless Oil

Uses

1-(Phenylmethoxy)-3-(2-propen-1-yloxy)-2-propanol (cas# 83016-75-5) is a compound useful in organic synthesis.

Upstream product

• 123-34-2 3-allyloxy-1,2-propanediol 
• 100-39-0 benzyl bromide 
• 106-92-3 Allyl glycidyl ether 
• 100-51-6 benzyl alcohol 
• 2930-05-4 Benzyloxymethyl-oxiran 
• 107-18-6 allyl alcohol 
• 1746-13-0 allyl phenyl ether 

Downstream Products

• 338458-96-1 6-benzyloxymethyl-2-iodomethyl-1,4-dioxane 
• 79494-95-4 2-benzyloxymethyl-6-hydroxymethyl-1,4-dioxane 
• 338458-98-3 2-acetoxymethyl-6-benzyloxymethyl-1,4-dioxane 
• 338458-99-4 6-benzyloxymethyl-2-p-nitrobenzoyloxymethyl-1,4-dioxane 

Relevant articles and documents

Regio/site-selective alkylation of substrates containing a: Cis -, 1,2- or 1,3-diol with ferric chloride and dipivaloylmethane as the catalytic system

In this study, we reported the regio/site-selective alkylation of substrates containing a cis-, 1,2- or 1,3-diol with FeCl3 as a key catalyst. A catalytic system consisting of FeCl3 (0.01-0.1 equiv.) and dipivaloylmethane (FeCl3/dipivaloylmethane = 1/2) was used to catalyze the alkylation in the presence of a base. The produced selectivities and isolated yields were similar to those obtained by methods using the same amount of FeL3 (L = acylacetone ligand) as the catalyst in most cases. The previously reported FeL3 catalysts for alkylation are not commercially available and have to be synthesized prior to use. In contrast, FeCl3 and dipivaloylmethane (Hdipm) are very common and inexpensive nontoxic reagents in the lab, thereby making the method much greener and easier to handle. Mechanism studies confirmed for the first time that FeCl3 initially reacts with two equivalents of Hdipm to form [Fe(dipm)3] in the presence of a base in acetonitrile, followed by the formation of a five or six-membered ring intermediate between [Fe(dipm)3] and two hydroxyl groups of the substrate. A subsequent reaction between the cyclic intermediate and the alkylating agent results in selective alkylation of the substrate.

Nucleophilic reactivity of ethers against terminal epoxides in the presence of BF3: A mechanistic study

In the presence of BF3, a series of symmetrical and unsymmetrical ethers reacted with epichlorohydrin and 2-[(benzyloxy)methyl] oxirane, two terminal epoxides, to afford 1-alkoxy-3-chloropropan-2-ol and 1-alkoxy-3-(benzyloxy)propan-2-ol. The cleavage of unsymmetrical ethers occurred via an SN2 or SN1 mechanism. Secondary epoxides did not give similar ring-opening products. Copyright

Highly efficient cleavage of epoxides catalyzed by B(C6F5)3

A highly effective protocol for ring opening of epoxides with allyl and propargyl alcohols, aniline and thiophenol in the presence of catalytic amounts of B(C6F5)3 has been developed. Benzyl, tetrahydropyranyl, tert-butyld