83039-57-0

Basic information

• Product Name: 2,5-Pyrrolidinedione, 1-[(4-methylbenzoyl)oxy]-
• CAS NO: 83039-57-0
• Molecular Formula: C12H11NO4
• Molecular Weight: 233.224
• Mol File: 83039-57-0.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: 2,5-Pyrrolidinedione, 1-[(4-methylbenzoyl)oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Pyrrolidinedione, 1-[(4-methylbenzoyl)oxy]-(83039-57-0)
• EPA Substance Registry System: 2,5-Pyrrolidinedione, 1-[(4-methylbenzoyl)oxy]-(83039-57-0)

Safety Data

• Hazardous Substances Data: 83039-57-0(Hazardous Substances Data)

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 201230-82-2 carbon monoxide 
• 29540-83-8 p-tolyl triflate 
• 814-49-3 diethyl chlorophosphate 
• 99-94-5 p-Toluic acid 
• 17592-54-0 2,5-dioxopyrrolidin-1-yl formate 
• 624-31-7 4-tolyl iodide 
• 104-87-0 4-methyl-benzaldehyde 
• 1634-04-4 tert-butyl methyl ether 
• 2524-64-3 chlorophosphoric acid diphenyl ester 
• 589-18-4 4-Methylbenzyl alcohol 

Downstream Products

• 5456-97-3 N-butyl-4-methylbenzamide 
• 2318-82-3 N-hydroxy-4-methylbenzamide 
• 5436-83-9 N-benzyl-4-methylbenzamide 
• 1415816-84-0 C₃₄H₃₆N₄O₆ 
• 1165802-20-9 C₄₁H₄₀N₂O₃ 

Relevant articles and documents

N -Heterocyclic carbene (NHC) catalyzed amidation of aldehydes with amines via the tandem N -hydroxysuccinimide ester formation

A facile method for the amidation of aldehydes by a cascade approach was developed. This methodology, reported for the first time, uses a N-heterocyclic carbene (NHC) as the catalyst, and N-hydroxysuccinimide (NHS) mediated synthesis of amides utilising TBHP as the oxidant. Various substituted aldehydes reacted smoothly with NHS giving the corresponding active esters in moderate to good yields, which facilely converted into amides in one pot. In addition, the drug moclobemide was synthesized to represent the practical utility of the developed methodology. This journal is

N-Doped Yellow TiO2 Hollow Sphere-Mediated Visible-Light-Driven Efficient Esterification of Alcohol and N-Hydroxyimides to Active Esters

Herein we report a simple synthetic protocol for N-doped yellow TiO2 (N-TiO2) hollow spheres as an efficient visible-light-active photocatalyst using aqueous titanium peroxocarbonate complex (TPCC) solution as precursor and NH4OH. In the developed strategy, the ammonium ion of TPCC and NH4OH acts as nitrogen source and structure-directing agent. The synthesized N-TiO2 hollow spheres are capable of promoting the synthesis of active esters of N-hydroxyimide and alcohol through simultaneous selective oxidation of alcohol to aldehyde followed by cross-dehydrogenative coupling (CDC) under ambient conditions upon irradiation of visible light. It is possible to develop a novel and cost-effective one-pot strategy for the synthesis of important esters and amides on gram scale using the developed strategy. The catalytic activity of N-TiO2 hollow spheres is much superior to that of other reported N-TiO2 samples as well as TiO2 with varying morphology.

Atmospheric oxidative catalyst-free cross-dehydrogenative coupling of aldehydes with N-hydroxyimides

Cross-dehydrogenative coupling (CDC) reactions of aldehydes with N-hydroxyimidates such as N-hydroxysuccinimide (NHSI), N-hydroxyphthalimide (NHPI) under catalyst-free conditions is described. Moreover, the desired products can be obtained simply by recrystallization from ethanol. This method is also applicable to the synthesis of amides in excellent yields. A radical mechanism of the type shown in Scheme 4 is proposed based upon the inhibition of the reaction in the presence of TEMPO.