831-00-5

Basic information

• Product Name: 2' 4'-DIMETHOXYPROPIOPHENONE 97
• Synonyms: 2' 4'-DIMETHOXYPROPIOPHENONE 97;1-(2,4-Dimethoxyphenyl)-1-propanone;Propan-1-one, 1-(2,4-dimethoxyphenyl)-;Propiophenone, 2',4'-dimethoxy-;1-(2,4-dimethoxyphenyl)propan-1-one;1,3-Dimethoxy-4-propionylbenzene;2',4'-Dimethoxypropiophenone 97%
• CAS NO: 831-00-5
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.22706
• EINECS: 212-601-7
• Product Categories: C11 to C12;Carbonyl Compounds;Ketones;Building Blocks;C11 to C12;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks
• Mol File: 831-00-5.mol
• Article Data: 11

Chemical Properties

• Melting Point: 76-80 °C(lit.)
• Appearance: /
• CAS DataBase Reference: 2' 4'-DIMETHOXYPROPIOPHENONE 97(CAS DataBase Reference)
• NIST Chemistry Reference: 2' 4'-DIMETHOXYPROPIOPHENONE 97(831-00-5)
• EPA Substance Registry System: 2' 4'-DIMETHOXYPROPIOPHENONE 97(831-00-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 831-00-5(Hazardous Substances Data)

Usage

Preparation

Preparation by reaction of dimethyl sulfate with respropiophenone in methanol, in the presence of aqueous sodium hydroxide solution (89%) ; in the presence of potassium hydroxide.

Upstream product

• 802294-64-0 propionic acid 
• 151-10-0 1,3-Dimethoxybenzene 
• 5792-36-9 2',4'-dihydroxypropiophenone 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 79-03-8 propionyl chloride 
• 137516-81-5 2-(2,4-dimethoxyphenyl)-2-ethyl-1,3-dioxolane 
• 50900-55-5 (E)-2,4-dimethoxy-1-(prop-1-en-1-yl)benzene 
• 150-19-6 O-methylresorcine 
• 108-46-3 recorcinol 
• 123-62-6 propionic acid anhydride 

Downstream Products

• 77942-21-3 3-(NN-dimethylamino)-2-methyl-1-(2,4-dimethoxyphenyl)propan-1-one 
• 84958-13-4 2-[(Z)-3-(2,4-Dimethoxy-phenyl)-pent-2-enyl]-2-methyl-cyclopentane-1,3-dione 
• 107496-14-0 [1-(2,4-Dimethoxy-phenyl)-prop-(E)-ylidene]-((S)-2-methoxymethyl-pyrrolidin-1-yl)-amine 
• 36680-47-4 di-methyl ether of 4-n-propyl resorcinol 
• 117844-88-9 2-Bromo-1-(2,4-dimethoxy-phenyl)-propan-1-one 
• 84226-08-4 N-((S)-1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-3-propyl-benzamide 
• 96897-98-2 2,6-dimethoxy-3-propylbenzoic acid 

Relevant articles and documents

Catalysis of the acylation of aromatic derivatives by metallic tosylates

A series of metallic tosylates were prepared by ultrasonic metal activation and were further used as efficient catalysts for the acylation of aromatic derivatives.

Acylation of aromatic ethers using different carboxylic acid anhydrides as acylating agents in the presence of nontoxic, noncorrosive resin amberlyst 15 as a solid acid catalyst

Friedel-Crafts acylation of aromatic ethers, anisole, 2-methoxynaphthalene, and dimethoxybenzenes with different acid anhydrides is carried out in the presence of an inexpensive and nonhazardous solid acid, Amberlyst 15. The catalyst is reusable, thus making the process environmentally friendly.

Studies towards the stereoselective α-hydroxylation of flavanones. Biosynthetic significance

The enolates of various propiophenones, chromanones, and also analogues of naturally occurring flavanones were stereoselectively hydroxylated at the ?-position, by employing commercially available enantiopure oxaziridines, to afford the desired ?-hydroxylated target molecules in good to exceptional stereoselectivities and in moderate to good chemical yields. A mechanistic rationale is presented to account for the stereoselectivities achieved. These in vitro results were tentatively related to the stereoselective biosynthesis of enantio-enriched dihydroflavonols while questions were raised about the authenticity of certain natural compounds. CSIRO 2008.