831-93-6Relevant articles and documents
PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
-
Page/Page column 142, (2020/01/11)
Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
Convenient synthesis of monoprotected 1,2-diols
Poppe,Recseg,Novak
, p. 3993 - 4000 (2007/10/03)
Reaction of the protected glycidol derivatives (1A-C) with a wide variety of Grignard reagents (2a-h) in the presence of catalytic amount of CuCN provided the corresponding monoprotected diol derivatives (3) in a highly regioselective manner.
A NEW METHOD FOR THE HYDROXYMETHYLATION OF CARBONYL COMPOUNDS
Imamoto, Tsuneo,Takeyama, Toshiaki,Yokoyama, Masataka
, p. 3225 - 3226 (2007/10/02)
Benzyl chloromethyl ether reacts with carbonyl compounds in the presence of SmI2 to afford alcohols (I), which are subsequently subjected to hydrogenolysis to yield diols (II).