83105-75-3Relevant articles and documents
Solid-Phase Synthesis of β-Lactams via the Miller Hydroxamate Approach
Meloni, Marco Massimiliano,Taddei, Maurizio
, p. 337 - 340 (2007/10/03)
(Matrix Presented) β-Lactams were prepared on solid phase starting from serine, threonine, or other β-hydroxyacids derived from naturally occurring amino acids and a resin bound hydroxylamine. The ring closure was carried out under Mitsunobu conditions. The amino group present on the β-lactam was used to assemble a short peptide. After a reductive cleavage with Sml2, β-lactam-containing peptides were obtained.
O-sulfated β-lactam hydroxamic acids (monosulfactams). Novel monocyclic β-lactam antibiotics of synthetic origin
Gordon,Ondetti,Pluscec,et al.
, p. 6053 - 6060 (2007/10/19)
-