83117-10-6

Basic information

• Product Name: (1beta,12alpha,15beta)-15-heptyl-1,11,12-trihydroxy-11,20-epoxypicras-3-ene-2,16-dione
• CAS NO: 83117-10-6
• Molecular Formula: C₂₇H₄₀O₇
• Molecular Weight: 476.6023
• Mol File: 83117-10-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 664.9°C at 760 mmHg
• Flash Point: 219.4°C
• Density: 1.27g/cm³
• Vapor Pressure: 1.64E-20mmHg at 25°C
• Refractive Index: 1.581
• CAS DataBase Reference: (1beta,12alpha,15beta)-15-heptyl-1,11,12-trihydroxy-11,20-epoxypicras-3-ene-2,16-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (1beta,12alpha,15beta)-15-heptyl-1,11,12-trihydroxy-11,20-epoxypicras-3-ene-2,16-dione(83117-10-6)
• EPA Substance Registry System: (1beta,12alpha,15beta)-15-heptyl-1,11,12-trihydroxy-11,20-epoxypicras-3-ene-2,16-dione(83117-10-6)

Safety Data

• Hazardous Substances Data: 83117-10-6(Hazardous Substances Data)

Usage

Description

(1beta,12alpha,15beta)-15-heptyl-1,11,12-trihydroxy-11,20-epoxypicras-3-ene-2,16-dione is a complex organic compound belonging to the class of picrasane-type diterpenoids. It features a heptyl chain, multiple hydroxyl groups, and an epoxide ring, and is naturally occurring in certain plants. (1beta,12alpha,15beta)-15-heptyl-1,11,12-trihydroxy-11,20-epoxypicras-3-ene-2,16-dione has been studied for its potential biological activities, such as anti-inflammatory, antimicrobial, and antitumor properties, making it a promising candidate for further research and development in pharmaceutical and medical fields.

Uses

Used in Pharmaceutical Industry:
(1beta,12alpha,15beta)-15-heptyl-1,11,12-trihydroxy-11,20-epoxypicras-3-ene-2,16-dione is used as a potential therapeutic agent for its anti-inflammatory, antimicrobial, and antitumor properties. Its unique chemical structure suggests that it may contribute to the development of new treatments for various diseases and conditions.
Used in Medical Research:
In the field of medical research, (1beta,12alpha,15beta)-15-heptyl-1,11,12-trihydroxy-11,20-epoxypicras-3-ene-2,16-dione is utilized for studying its pharmacological activities and exploring its potential as a lead compound for drug development. This can aid in understanding its mechanisms of action and optimizing its therapeutic potential.

Upstream product

• 83137-29-5 C₃₄H₅₆O₉Si₂ 
• 4616-50-6 chaparrin 
• 83117-01-5 C₃₂H₅₆O₇Si₂ 
• 83137-28-4 C₃₅H₆₄O₇Si₃ 
• 83117-07-1 C₃₄H₅₈O₉Si₂ 
• 83117-03-7 C₃₅H₆₄O₈Si₃ 
• 83117-04-8 C₄₀H₇₂O₉Si₃ 
• 116064-14-3 C₃₆H₆₂O₇Si₂ 
• 4282-40-0 1-Iodoheptane 
• 4616-50-6 (-)-chaparrinone 
• 83117-01-5 2,11-di-t-butyldimethylsilyl chaparrin 
• 116064-10-9 C₃₆H₆₄O₇Si₂ 
• 83137-28-4 2,11-di-t-butyldimethylsilyl-trimethylsilyl chaparrin 
• 83117-06-0 15β-n-heptyl-2,11,di-t-butyldimethylsilyl-1-trimethylsilyl chaparrin 

Relevant articles and documents

Biologically active quassinoids : synthetic methodology for the conversion of chaparrin into glaucarubolone esters and quassinoid analogs1 1 For previous paper in this series see: C. Moretti, S. Bhatnagar, J.C. Beloeil and J. Polonsky, J. Nat. Prods., 49, 440 (1986)

Biologically inactive but easily available chaparrin 2a has been converted into potent antileukemic C-15 esters of glaucarubolone 2b and quassinoid analogs in which the C-15 ester side chain has been replaced by an alkyl or alkenyl group.The synthetic methodology developed has been applied to the preparation of C-15 ester derivatives 15, 16, 17 and quassinoid analogs 12, 13 and 14.