83191-25-7

Basic information

• Product Name: N-(2,2,2-trichloro-1-ethoxyethyl)benzenesulfonamide
• CAS NO: 83191-25-7
• Molecular Weight: 332.635
• Mol File: 83191-25-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(2,2,2-trichloro-1-ethoxyethyl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,2,2-trichloro-1-ethoxyethyl)benzenesulfonamide(83191-25-7)
• EPA Substance Registry System: N-(2,2,2-trichloro-1-ethoxyethyl)benzenesulfonamide(83191-25-7)

Safety Data

• Hazardous Substances Data: 83191-25-7(Hazardous Substances Data)

Upstream product

• 83191-20-2 N-(2,2,2-trichloro-1-acetoxyethyl)benzenesulfonamide 
• 75457-08-8 N-(2,2,2-trichloro-1-hydroxyethyl)benzenesulfonamide 
• 83790-88-9 N-chloro-N-(2,2,2-trichloro-1-acetoxyethyl)benzenesulfonamide 
• 55596-11-7 N-(2,2,2-trichloroethylidene)benzenesulfonamide 
• 64-17-5 ethanol 
• 129633-30-3 N-(2,2,2-Trichloro-1-methoxy-ethyl)-benzenesulfonamide 

Downstream Products

• 83191-20-2 N-(2,2,2-trichloro-1-acetoxyethyl)benzenesulfonamide 
• 75457-08-8 N-(2,2,2-trichloro-1-hydroxyethyl)benzenesulfonamide 
• 136454-70-1 1-(Benzenesulfonylamido)-1-phenyl-2,2,2-trichloroethane 
• 255048-78-3 N-[2,2,2-trichloro-1-(4-methylphenyl)ethyl]benzenesulfonamide 

Relevant articles and documents

Hydrolysis of N-(2,2,2-trichloroethyl)arenesulfonamides

The direction of alkaline hydrolysis of N-(2,2,2-trichloro-1-R-ethyl)arenesulfonamides depends on the R substituent in the α-position with respect to the nitrogen atom. Substituents R having an n-donor heteroatom X promote cleavage of the C-N and C-X bonds to release the corresponding sulfonamide. Alkaline hydrolysis of N-(1-aryl-2,2,2-trichloroethyl)arenesulfonamides occurs chemoselectively at the trichloromethyl group. This reaction can be regarded as a preparative route to N-arylsulfonyl-α-arylglycines.

SYNTHESIS OF HETEROORGANIC DERIVATIVES OF BENZENESULFONAMIDE

The reaction of trichloroethylene with N,N-dichlorobenzenesulfonamide and proton-donor compounds, like oximes, carboxylic acids, thiols, amines, phenylhydrazine, or phenylurea, leads in one step to the corresponding heteroorganic derivatives of benzenesul