83196-21-8Relevant articles and documents
Synthesis method of substituted urea compound
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Paragraph 0034-0039; 0084-0089, (2021/03/31)
The invention discloses a synthesis method of a substituted urea compound, which comprises the following steps: stirring aldehyde, N-aryl urea, trichlorosilane and Lewis base in an organic solvent ata temperature range of -20 DEG C to room temperature for
Parallel synthesis of ureas and carbamates from amines and CO2 under mild conditions
Peterson, Scott L.,Stucka, Sabrina M.,Dinsmore, Christopher J.
supporting information; experimental part, p. 1340 - 1343 (2010/06/15)
"Chemical Equation Presented" A mild and efficient library synthesis technique has been developed for the synthesis of ureas and carbamates from carbamic acids derived from the DBU-catalyzed reaction of amines and gaseous carbon dioxide. Carbamic acids derived from primary amines reacted with Mitsunobu reagents to generate isocyanates in situ which were condensed with primary and secondary amines to afford the desired ureas. Similarly, carbamic acids from secondary amines reacted with alcohols activated with Mitsunobu reagents to form carbamates.
Efficient Synthesis of Polysubstituted Acylguanidines and Guanylureas
Katritzky, Alan R.,Rogovoy, Boris V.,Cai, Xiaohong,Kirichenko, Nataliya,Kovalenko, Katherine V.
, p. 309 - 313 (2007/10/03)
(Benzotriazol-1-yl)carboximidamides were applied for the preparation of polysubstituted acylguanidines and guanylureas. The reaction sequence utilized mild conditions and gave high yields for final compounds and intermediates. The protocol developed allows for variation of the substituents at all positions of the products.