832-41-7

Basic information

• Product Name: N-(ethoxymethyl)-4-methylbenzenesulfonamide
• Synonyms: N-(ethoxymethyl)-4-methylbenzenesulfonamide
• CAS NO: 832-41-7
• Molecular Weight: 229.3
• Mol File: 832-41-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-(ethoxymethyl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(ethoxymethyl)-4-methylbenzenesulfonamide(832-41-7)
• EPA Substance Registry System: N-(ethoxymethyl)-4-methylbenzenesulfonamide(832-41-7)

Safety Data

• Hazardous Substances Data: 832-41-7(Hazardous Substances Data)

Upstream product

• 106-45-6 para-thiocresol 
• 109-85-3 2-methoxyethylamine 
• 107-25-5 methoxyethene 
• 70-55-3 toluene-4-sulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 627-42-9 2-chloroethyl methyl ether 

Downstream Products

• 14627-24-8 3-tosyl-1,3-oxazolidine 
• 17900-53-7 2-methyl-1-(4-methylbenzenesulfonyl)-1H-pyrrole 
• 837-10-5 N-(2-methoxy-ethyl)-N-nitroso-toluene-4-sulfonamide 

Relevant articles and documents

Electrochemical C?H Amidation of Heteroarenes with N-Alkyl Sulfonamides in Aqueous Medium

The construction of C?N bonds by free radical reactions represents a powerful synthetic approach for direct C?H amidations of arenes or heteroarenes. Developing efficient and more environmentally friendly synthetic methods for C?H amidation reactions remains highly desirable. Herein, metal-free electrochemical oxidative dehydrogenative C?H amidations of heteroarenes with N-alkylsulfonamides have been accomplished. The catalyst- and chemical-oxidant-free C?H amidation features an ample scope and employs electricity as the green and sole oxidant. A variety of heteroarenes, including indoles, pyrroles, benzofuran and benzothiophene, thereby underwent this C(sp2)?H nitrogenation. Cyclic voltammetry studies and control experiments provided evidence for nitrogen-centered radicals being directly generated under metal-free electrocatalysis.

Metal-free I2O5-mediated direct construction of sulfonamides from thiols and amines

A simple and convenient method has been developed for the construction of sulfonamides via I2O5-mediated sulfonylation of amines with arylthiols. The present protocol provides an attractive approach to sulfonamides in moderate to good yields from readily accessible and easy to handle starting materials under mild and metal-free conditions.

ALUMINA CATALYZED TRANSFORMATION OF O-(3-OXOBUTYL) URETHANES

The alumina-catalyzed transformations of urethane to a secundary amine and a sulfonyl urethane to a sulfonamide are described.Alumina is also shown to catalyze the conjugate addition of p-toluenesulfonamide to methyl vinyl ketone.