83237-49-4 Usage
Chemical Properties
White powder
Uses
2-(3-(Carboxymethyl)-4-(phenylthio)-phenyl)propanoic Acid is an intermediate used to prepare Zaltoprofen (Z146000) which is anti-inflammatory.
Check Digit Verification of cas no
The CAS Registry Mumber 83237-49-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,2,3 and 7 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 83237-49:
(7*8)+(6*3)+(5*2)+(4*3)+(3*7)+(2*4)+(1*9)=134
134 % 10 = 4
So 83237-49-4 is a valid CAS Registry Number.
InChI:InChI=1/C17H16O4S/c1-11(17(20)21)12-7-8-15(13(9-12)10-16(18)19)22-14-5-3-2-4-6-14/h2-9,11H,10H2,1H3,(H,18,19)(H,20,21)
83237-49-4Relevant articles and documents
Preparation of 2-(10,11-dihydro-10-oxodibenzo-[b,f]thiepin-2-yl) propionic acid
-
, (2008/06/13)
PCT No. PCT/JP97/02922 Sec. 371 Date Feb. 17, 1999 Sec. 102(e) Date Feb. 17, 1999 PCT Filed Aug. 22, 1997 PCT Pub. No. WO98/07717 PCT Pub. Date Feb. 26, 1998A process for preparation of 2-(10,11-dihydro-10-oxodibenzo[b,f]thiepin-2-yl)propionic acid (i.e., Zaltoprofen) is performed by subjecting 2-(4-amino-3-carboxy-methylphenyl)propionic acid or its salt to diazotization and subsequent reaction with thiophenol to produce 2-(3-carboxymethyl-4-phenylthiophenyl)propionic acid or its salt, and subjecting the product to cyclization reaction. Other related processes and related compounds are also disclosed.
