834-25-3

Basic information

• Product Name: benzyl p-tolyl ether
• Synonyms: benzyl p-tolyl ether;Benzyl p-cresyl ether;1-(Benzyloxy)-4-methylbenzene;4-Methyl-1-benzyloxybenzene;p-Tolylbenzyl ether
• CAS NO: 834-25-3
• Molecular Formula: C₁₄H₁₄O
• Molecular Weight: 198.26036
• EINECS: 212-636-8
• Mol File: 834-25-3.mol
• Article Data: 52

Chemical Properties

• Boiling Point: 308.3°C at 760 mmHg
• Flash Point: 120.4°C
• Appearance: /
• Density: 1.041g/cm³
• Vapor Pressure: 0.00125mmHg at 25°C
• Refractive Index: 1.567
• CAS DataBase Reference: benzyl p-tolyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl p-tolyl ether(834-25-3)
• EPA Substance Registry System: benzyl p-tolyl ether(834-25-3)

Safety Data

• Hazardous Substances Data: 834-25-3(Hazardous Substances Data)

Usage

General Description

Benzyl p-tolyl ether is an organic compound with the chemical formula C14H14O. It is a colorless liquid that is commonly used as a solvent in various industrial processes and can be found in some consumer products. Benzyl p-tolyl ether is also used as a building block in the synthesis of pharmaceuticals and other organic compounds. It has a sweet, floral odor and is flammable, making it important to handle with care. The compound is often used as a fragrance ingredient and in the production of flavorings and perfumes.

InChI:InChI=1/C14H14O/c1-12-7-9-14(10-8-12)15-11-13-5-3-2-4-6-13/h2-10H,11H2,1H3

Upstream product

• 106-44-5 p-cresol 
• 3204-68-0 benzyldimethylphenylammonium chloride 
• 100-44-7 benzyl chloride 
• 1192-96-7 potassium p-cresolate 
• 1121-70-6 sodium 4-methylphenoxide 
• 108-88-3 toluene 
• 78-32-0 tri-p-cresyl phosphate 
• 100-39-0 benzyl bromide 
• 69002-30-8 4-Trimethylstannyloxy-toluol 
• 100-51-6 benzyl alcohol 
• 140-39-6 1-acetoxy-4-methylbenzene 
• 22900-27-2 benzylphenylmethyl sulfonium fluoroborate 
• 2830-53-7 1-(benzyloxy)-2-bromo-4-methylbenzene 
• 53772-44-4 benzyloxydiphenylphosphine 

Downstream Products

• 836-43-1 4-benzyloxybenzyl alcohol 
• 15539-77-2 4-nitrobenzyl nitrate 
• 1517-63-1 4-methylphenyl(phenyl)methanol 
• 716-96-1 2-benzyl-4-methylphenol 
• 106-44-5 p-cresol 
• 51009-90-6 2,7-dimethyl-9-phenyl-xanthene 
• 108-88-3 toluene 
• 36441-31-3 1-benzyl-2-naphthol 
• 30091-02-2 3-Methyl-4-benzylphenol 
• 100717-11-1 benzyl 2-iodo-4-methylphenyl ether 
• 6627-39-0 2,6-dibenzyl-4-methylphenol 
• 609-93-8 2,6-dinitro-p-cresol 
• 100-52-7 benzaldehyde 
• 623-05-2 (4-hydroxyphenyl)methanol 

Relevant articles and documents

Towards ortho-selective electrophilic substitution/addition to phenolates in anhydrous solvents

Alkyl-substituted Li-phenolates with BnBr in water solution lead to a mixture of o- and p-Bn-substituted phenols together with a substantial amount of phenol Bn ether. In CPME, and especially in toluene with 1–2 equivalents of ether or alcohol additives, ortho-selective alkylation is achieved. In the case of o,o,p-tri- and o,o-di-substituted phenols dearomatization occurs affording o-Bn-substituted alkyl cyclohexadienones with yields up to 92% with an o/p ratio up to 90/1.

Application of iron (III) complex containing 1,3-di-tert-butyl imidazole cations in synthesis of aryl benzyl ether compounds

The invention discloses an application of an iron (III) complex containing 1,3-di-tert-butyl imidazole cations in synthesis of aryl benzyl ether compounds, and particularly relates to a method for synthesizing corresponding aryl benzyl ether compounds by taking di-tert-butyl peroxide as an oxidizing agent and carrying out oxidative coupling reaction on phenolic compounds and toluene compounds. According to the method, the iron (III) complex is used as the catalyst for the first time, and oxidative coupling of the phenolic compound and the toluene compound is realized. The method is the first oxidative coupling reaction of phenolic compounds and benzyl C(sp3)-H bonds, and a new method is provided for synthesizing aryl benzyl ether compounds. Compared with an existing synthesis method, the method provided by the invention avoids using toxic and polluting halogenated hydrocarbon and strong base, has better atom economy, and conforms to the development concept of green synthetic chemistry.

An alternative route for boron phenoxide preparation from arylboronic acid and its application for C[sbnd]O bond formation

An efficient synthetic route to benzyl phenyl ether preparation has been successfully developed via a one-pot synthetic protocol utilizing a combination of arylboronic acids, hydrogen peroxide (H2O2), and benzyl halides. The whole procedure consists of two consecutive reactions, formation of boron phenoxide from arylboronic acids and its nucleophilic attack. A simple operation under mild conditions such as room-temperature ionic liquid (choline hydroxide), aerobic environment, and absence of metal- and base-catalysts has been employed. Expansion to utilize benzyl surrogates was also successfully accomplished.