83420-59-1

Basic information

• Product Name: 4-(4-Iodophenyl)pyridine
• Synonyms: 4-(4-Iodophenyl)pyridine
• CAS NO: 83420-59-1
• Molecular Formula: C₁₁H₈IN
• Molecular Weight: 281.09
• Mol File: 83420-59-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 204℃
• Appearance: /
• Density: 1.653
• CAS DataBase Reference: 4-(4-Iodophenyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Iodophenyl)pyridine(83420-59-1)
• EPA Substance Registry System: 4-(4-Iodophenyl)pyridine(83420-59-1)

Safety Data

• Hazardous Substances Data: 83420-59-1(Hazardous Substances Data)

Usage

General Description

4-(4-Iodophenyl)pyridine is an organic compound with the molecular formula C11H8IN, which indicates that it consists of 11 carbon atoms, 8 hydrogen atoms, 1 iodine atom and 1 nitrogen atom. It contains an iodinated phenyl ring attached to a pyridine ring, and it appears as an off-white crystalline powder. This chemical is primarily used in research as a synthetic intermediate for the fabrication of more complex substances, notably including pharmaceuticals. Its iodination makes it highly reactive and susceptible to undergoing various chemical transformations, such as coupling reactions.

Upstream product

• 13296-04-3 4-(pyridin-4-yl)aniline 
• 624-38-4 para-diiodobenzene 
• 1692-15-5 4-pyridylboronic acid 

Downstream Products

• 552272-74-9 2,4'-(4-ethynylphenyl)bipyridine 

Relevant articles and documents

Synthesis and X-ray crystallographic analysis of chiral pyridyl substituted carbocyclic molecular clefts

Ditopic symmetrical bis(pyridyl) ligands incorporating the chiral dibenzobicyclo[b,f][3.3.1]nona-5a,6a-diene-6,12-dione cleft have been synthesised and characterised by NMR spectroscopy, mass spectrometry and X-ray crystallography. The ligands, which inco

Stereoselective association of binuclear metallacycles in coordination polymers

A series of structurally related binuclear metallacycles Cd(NO3)2L]2, where L is an angular exobidentate ligand, have been synthesized. Each metallacycle contains two coordinatively unsaturated, chiral metal centers within a single molecule, and the assembly of these metallacycles into polymeric framework structures has been studied systematically for the first time. Stereoselective homochiral association of [Cd(NO3)2L]2 leads to the formation of helical coordination polymers, whereas meso type association results in nonhelical chain structures. The type of stereoselective aggregation depends on the conditions of self-assembly as well as on ligand functionality. Both helical and nonhelical polymeric complexes have been isolated for the metallacycle [Cd(NO3)2(2,4′-pyacph)]2 (2,4′-pyacph = 2,4′-(4-ethynylphenyl)bipyridyl). Homochiral association results in the formation of helical [Cd(NO3)]∞ chains which link the binuclear [Cd(NO3)2(2,4′-pyacph)]2 metallacycles into racemic two-dimensional sheets which contain both P and M [Cd(NO3)]∞ helices. In contrast, meso-association leads to the formation of nonhelical one-dimensional chains. It is shown that the product of homochiral association is predominately formed at room temperature and that of meso-association is generated at elevated temperatures. Thus, it may be concluded that the homochiral association appears to be energetically less favorable than the meso-association, a conclusion that has been confirmed by theoretical calculations of the crystal lattice energy. Several high-yield syntheses of bipyridyl-type ligands used for metallacyclic assembly are also reported.