83421-78-7Relevant articles and documents
Chiral phosphoric acid catalyzed enantioselective annulation of acyclic enecarbamates to: In situ -generated ortho -quinone methides
Gharui, Chandan,Singh, Shreya,Pan, Subhas Chandra
, p. 7272 - 7276 (2017/09/25)
The first organocatalytic asymmetric reaction of acyclic enecarbamates with o-quinone methides is disclosed. BINOL-based phosphoric acid catalysts were found to be suitable for the annulation reaction. With 10 mol% of the TRIP catalyst, high yields as well as excellent diastereo- and enantioselectivities are achieved for a variety of 2,3,4-trisubstituted chroman products.
Synthesis and Evaluation of Ureido- and Vinylureidopenicillins as Inhibitors of Intraruminal Lactic Acid Production
Clark, Robin D.,Caroon, Joan M.,Harrison, Ian T.,Kluge, Arthur F.,Unger, Stefan H.,et al.
, p. 1250 - 1253 (2007/10/02)
A series of 14 vinylureidopenicillins and a series of 9 ureidopenicillins were prepared by reaction of 6-aminopenicillanic acid with vinyl isocyanates and isocyanates.These compounds were evaluated for their potential to protect ruminants against lactic a