834918-59-1

Basic information

• Product Name: Thymidine, 3'-azido-3'-deoxy-, 5'-(phenyl phosphonate)
• CAS NO: 834918-59-1
• Molecular Formula: C16H18N5O6P
• Molecular Weight: 407.323
• Mol File: 834918-59-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Thymidine, 3'-azido-3'-deoxy-, 5'-(phenyl phosphonate)(CAS DataBase Reference)
• NIST Chemistry Reference: Thymidine, 3'-azido-3'-deoxy-, 5'-(phenyl phosphonate)(834918-59-1)
• EPA Substance Registry System: Thymidine, 3'-azido-3'-deoxy-, 5'-(phenyl phosphonate)(834918-59-1)

Safety Data

• Hazardous Substances Data: 834918-59-1(Hazardous Substances Data)

Upstream product

• 616235-20-2 C₄₀H₄₂N₁₀O₁₄P₂ 
• 124930-59-2 3'-azido-3'-deoxythymidin-5'-yl H-phosphonate monoester 
• 108-95-2 phenol 
• 3426-89-9 phenyl phosphorodichloridite 
• 30516-87-1 3'-azido-2',3'-deoxythymidine 
• 4712-55-4 diphenyl hydrogen phosphite 

Downstream Products

• 142629-81-0 So₂₂₁ 
• 1162085-77-9 3'-azido-3'-deoxythymidin-5'-yl 2-methylpyridin-3-yl phenyl phosphate 
• 1162085-81-5 3'-azido-3'-deoxythymidin-5'-yl 6-methylpyridin-3-yl phenyl phosphate 
• 1162085-48-4 3'-azido-3'-deoxythymidin-5'-yl phenyl pyridin-4-yl phosphate 
• 1162085-44-0 3'-azido-3'-deoxythymidin-5'-yl phenyl pyridin-3-yl phosphate 
• 616235-19-9 C₃₉H₃₈Cl₂N₁₀O₁₃P₂ 
• 616235-18-8 C₃₇H₄₂Cl₂N₁₀O₁₃P₂ 
• 834918-68-2 C₁₆H₁₇ClN₅O₆P 
• 879688-49-0 Phosphoric acid (2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester 4-nitro-benzyl ester phenyl ester 
• 219909-16-7 Phosphoric acid (2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester phenyl ester 
• 879688-32-1 3'-azido-3'-deoxythymidin-5'-yl phenyl hydroxy(4-methoxyphenyl)methanephosphonate 
• 879688-30-9 3'-azido-3'-deoxythymidin-5'-yl phenyl hydroxy(phenyl)methanephosphonate 
• 879688-34-3 3'-azido-3'-deoxythymidin-5'-yl phenyl hydroxy(4-nitrophenyl)methanephosphonate 
• 879688-33-2 3'-azido-3'-deoxythymidin-5'-yl phenyl hydroxy(4-chlorophenyl)methanephosphonate 

Relevant articles and documents

Aryl nucleoside H-phosphonates. Part 16: Synthesis and anti-HIV-1 activity of di-aryl nucleoside phosphotriesters

Di-aryl nucleoside phosphotriesters have been explored as a new type of pronucleotides for the purpose of anti-HIV-1 therapy and efficient synthetic protocols, based on H-phosphonate chemistry, have been developed for the preparation of this class of comp

One-pot synthesis of aryl phosphoramidate derivatives of AZT/d4T as anti-HIV prodrugs

Arbuzov reaction of aryl phosphorodichloridite with mixture of one equivalent of AZT or d4T and one equivalent of tert-butyl alcohol led to the corresponding AZT/d4T aryl H-phosphonate diesters, and the following reaction of the H-phosphonate diesters wit

Aryl H-phosphonates. 14. Synthesis of new nucleotide analogues with phosphonate-phosphate internucleosidic linkage

(Equation presented) Aryl nucleoside H-phosphonates 3 and aryl nucleoside P-acylphosphonates 4, generated in situ from the appropriate H-phosphonate 1 and acylphosphonate monoesters 2, respectively, reacted rapidly in the presence of tertiary amines to pr