83492-23-3

Basic information

• Product Name: 5-(3-Bromo-quinolin-2-yl)-2-phenyl-thiazol-4-one
• CAS NO: 83492-23-3
• Molecular Weight: 383.268
• Mol File: 83492-23-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(3-Bromo-quinolin-2-yl)-2-phenyl-thiazol-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-Bromo-quinolin-2-yl)-2-phenyl-thiazol-4-one(83492-23-3)
• EPA Substance Registry System: 5-(3-Bromo-quinolin-2-yl)-2-phenyl-thiazol-4-one(83492-23-3)

Safety Data

• Hazardous Substances Data: 83492-23-3(Hazardous Substances Data)

Upstream product

• 22615-00-5 3-bromoquinoline N-oxide 
• 827-46-3 2-phenyl-thiazol-4-one 

Relevant articles and documents

Studies on Tertiary Amine Oxides. LXXIV. Reactions of Aromatic N-Oxides with 2-Phenyl-2-Thiazolin-4-one in the Presence of Acetic Anhydride

Quinoline 1-oxides (1a-e) readily react with 2-phenyl-2-thiazolin-4-one (2) in acetic anhydride at room temperature to afford the corresponding 5-(2-quinolyl)thiazolones (3a-e) in good yields.The reaction of 4-chloroquinoline 1-oxide (1f) gives 4-acetoxy-5-(4-chloro-2-quinolyl)-2-phenylthiazole (4).Hydrolyses of 1a-e with 48percent hydrobromic acid under reflux give 2-quinolinemethanethiols as the hydrobromides (6a-e).Similar results were obtained from the reaction of isoquinoline 2-oxide (7), but pyridine 1-oxide was unreactive.Keywords --- aromatic N-oxide; 2-phenyl-2-thiazolin-4-one; 2-phenyl-5-(2-quinolyl)-2-thiazolin-4-ones; 2-quinolinemethanethiols; 5-(1-isoquinolyl)-2-phenyl-2-thiazolin-4-one; 1-isoquinolinemethanethiol; nucleophilic substitution