835-31-4Relevant articles and documents
Preparation method of naphazoline hydrochloride
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Paragraph 0015; 0018-0019, (2021/01/24)
The invention relates to the technical field of organic synthesis, in particular to a preparation method of naphazoline hydrochloride, which comprises the following steps: by using alpha-naphthylacetic acid, ethylenediamine and acetone as raw materials, carrying out condensation, cyclization, salification and the like to prepare 4, 5-dihydro-2-(1-naphthyl methyl)-1H-imidazole hydrochloride. Alpha-naphthylacetic acid, ethylenediamine and acetone are used as raw materials to prepare the target product, and the raw materials are easy to obtain and low in price. Condensation, cyclization and salification are adopted, the operation reaction conditions are mild, a large number of side reactions are avoided, and the high yield is obtained. The preparation process is high in coherence, short in time consumption and more efficient and thorough in reaction. The preparation process is simple, reaction conditions are mild, and environmental pollution is avoided.
Colloid and nanosized catalysts in organic synthesis: XIII. Synthesis of 2-R-2-imidazolines catalyzed by copper and iron oxide nanoparticles
Popov,Mokhov,Kalitina
, p. 281 - 285 (2016/04/20)
The reaction of carboxylic acids with ethylenediamine catalyzed by copper or iron oxide nanoparticles proceeds at 80°C with azeotropic water distilling off during 2-8 h to form 2-R-2-imidazolines. Acyl and diacyl derivatives of ethylenediamine are formed in the reaction as side products.
Feed additive for improving growth in agricultural animals
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, (2008/06/13)
By using α-mimetics, particularly compounds of general formulae I to III and the compounds listed in Table I, as feed additives in fattening animals, it has surprisingly been possible to improve the daily weight gain, the utilisation of fodder and the ratio of muscle to fat in favor of the proportion of muscle and protein.