83520-06-3

Basic information

• Product Name: 2-(N,N-dimethylacetamidino)-2',5-dichlorobenzophenone
• Synonyms: 2-(N,N-dimethylacetamidino)-2',5-dichlorobenzophenone
• CAS NO: 83520-06-3
• Molecular Weight: 335.233
• Mol File: 83520-06-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(N,N-dimethylacetamidino)-2',5-dichlorobenzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(N,N-dimethylacetamidino)-2',5-dichlorobenzophenone(83520-06-3)
• EPA Substance Registry System: 2-(N,N-dimethylacetamidino)-2',5-dichlorobenzophenone(83520-06-3)

Safety Data

• Hazardous Substances Data: 83520-06-3(Hazardous Substances Data)

Upstream product

• 127-19-5 N,N-dimethyl acetamide 
• 2958-36-3 (2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone 

Downstream Products

• 83520-07-4 2-thioacetamido-2',5-dichlorobenzophenone 
• 64194-72-5 2',5-dichloro-2-<3-<<(phthaloylglycyl)amino>methyl>-5-methyl-4H-1,2,4-triazol-4-yl>benzophenone 
• 64348-20-5 2',5-dichloro-2-<3-<(α-azidoacetamido)methyl>-5-methyl-4H-1,2,4-triazol-4-yl>benzophenone 
• 64194-76-9 2',5-dichloro-2-<3-<(α-chloroacetamido)methyl>-5-methyl-4H-1,2,4-triazol-4-yl>benzophenone 
• 64194-73-6 2',5-dichloro-2-(3-glycylaminomethyl-5-methyl-4H-1,2,4-triazol-4-yl)-benzophenone 
• 64215-83-4 2',5-dichloro-2-<3-<(phenylalanylamino)methyl>-5-methyl-4H-1,2,4-triazol-4-yl>benzophenone 
• 64195-39-7 2',5-dichloro-2-<3-<<(phthaloyl-L-phenylalanyl)amino>methyl>-5-methyl-4H-1,2,4-triazol-4-yl>benzophenone 
• 64194-71-4 2',5-dichloro-2-<3-(aminomethyl)-5-methyl-4H-1,2,4-triazol-4-yl>benzophenone dihydrobromide 
• 83520-05-2 3-<<(benzyloxycarbonyl)glycyl>amino>-6-chloro-4-(2-chlorophenyl)-3,4-dihydro-4-hydroxy-2-methylquinazoline 
• 83520-17-6 2',5-dichloro-2-<3-<<(benzyloxycarbonyl)amino>methyl>-5-methyl-4H-1,2,4-triazol-4-yl>benzophenone 

Relevant articles and documents

Amino acid amide derivatives of 2-[3-(aminomethyl)-4H-1,2,4-triazol-4-yl]benzophenones, a novel class of annelated peptidoaminobenzophenones

A series of the title compounds was prepared via condensation of the 3-(aminomethyl)triazolylbenzophenone with N-protected amino acids, followed by deprotection, amination of the 3-[(chloroacetamido)methyl]triazolylbenzophenone, or reduction of the relevant azide derivative. Some of the title compounds were also derived directly from the quinazolines by acid-induced rearrangement, followed by deprotection. These new amino acid amide derivatives of the triazolylbenzophenones were evaluated for central nervous system (CNS) activity. Members of this class of compounds exhibited a high level of CNS activities. For example, 2',5-dichloro-2-[3-[(glycylamino)methyl]-5-methyl-4H-1,2,4-triazol-4-yl ]benzophenone was as active as triazolam, with an ED50 of 0.58 mg/kg (mice, po), against antifighting activity in the foot shock-induced fighting test. Other triazolylbenzophenone derivatives showed similar pharmacological activities.