83590-77-6 Usage
Description
4-HydroxyMethyl-3-MethOxyPhenoxyAcetic Acid, also known as 4-HMMP, is an organic compound with the chemical formula C9H10O6. It is characterized by the presence of a hydroxymethyl group, a methoxyphenoxy group, and an acetic acid moiety. This molecule exhibits unique chemical properties and reactivity, making it a versatile building block in various chemical and pharmaceutical applications.
Uses
Used in Solid Phase Peptide Synthesis (SPPS):
4-HydroxyMethyl-3-MethOxyPhenoxyAcetic Acid is used as an acid-labile resin linkage agent in Solid Phase Peptide Synthesis (SPPS). It is particularly suitable for the preparation of peptide fragments that have t-butyl (tBu)-based side chain protective groups. The acid-labile nature of 4-HMMP allows for the efficient release of the synthesized peptide from the resin support under mild acidic conditions, minimizing the risk of side reactions and degradation.
In the pharmaceutical industry, 4-HMMP can be utilized as a key intermediate in the synthesis of various bioactive peptides and peptidomimetics. Its unique structure and reactivity enable the development of novel therapeutic agents with improved pharmacokinetic properties and enhanced biological activity.
Additionally, 4-HMMP can be employed in the development of new resin materials for SPPS, offering improved stability, selectivity, and compatibility with a wide range of synthetic strategies. This can lead to more efficient and streamlined peptide synthesis processes, ultimately facilitating the discovery and production of new peptide-based drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 83590-77-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,5,9 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 83590-77:
(7*8)+(6*3)+(5*5)+(4*9)+(3*0)+(2*7)+(1*7)=156
156 % 10 = 6
So 83590-77-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H12O5/c1-14-9-4-8(15-6-10(12)13)3-2-7(9)5-11/h2-4,11H,5-6H2,1H3,(H,12,13)
83590-77-6Relevant articles and documents
Preparation method of 4-hydroxymethyl-3-methoxyphenoxyacetic acid
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Paragraph 0086; 0089; 0082, (2018/05/16)
The invention discloses a preparation method of 4-hydroxymethyl-3-methoxyphenoxyacetic acid, comprising the steps of a) subjecting the start material 2,4-dihydroxybenzaldehyde and halogenated ethyl acetate to nucleophilic substitution reaction under the a
