835925-56-9Relevant articles and documents
α-Cycloalkyl-substituted ω-keto-dicarboxylic acids as lipid regulating agents
Bell, Roel P.L.,Verdijk, Dennis,Relou, Mike,Smith, Dennis,Regeling, Henk,Ebbers, Eelco J.,C. Leemhuis, Frank M.,Oniciu, Daniela C.,Cramer, Clay T.,Goetz, Brian,Pape, Michael E.,Krause, Brian R.,Dasseux, Jean-Louis
, p. 223 - 236 (2007/10/03)
A series of cycloalkyl-substituted oxo-alkanedicarboxylic acids have been prepared by the TosMIC methodology departing from haloalkyl-substituted cycloalkylcarboxylic esters. cyclopropyl derivatives showed IC50 activity in the 0.3-1.0 μM range
