836-12-4 Usage
General Description
The chemical compound, 1,4-dihydro-4-oxo-6-(trifluoromethyl)-2-pyrimidinylthio]-acetic acid, is a thioester derivative of an oxopyrimidine compound. [[1,4-DIHYDRO-4-OXO-6-(TRIFLUOROMETHYL)-2-PYRIMIDINYL]THIO]-ACETIC ACID contains a trifluoromethyl group, which makes it highly electronegative and reactive. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals due to its functional groups and reactivity. The thioester group in this compound makes it useful in the formation of peptide bonds and other important chemical reactions. Additionally, the trifluoromethyl group can impart unique chemical properties to the compound, making it desirable for specific applications in drug design and synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 836-12-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,3 and 6 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 836-12:
(5*8)+(4*3)+(3*6)+(2*1)+(1*2)=74
74 % 10 = 4
So 836-12-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H5F3N2O3S/c8-7(9,10)3-1-4(13)12-6(11-3)16-2-5(14)15/h1H,2H2,(H,14,15)(H,11,12,13)
836-12-4Relevant articles and documents
INHIBITORS OF α-AMINO-β-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE
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Paragraph 00528, (2020/06/10)
The present disclosure discloses compounds capable of modulating the activity of α-amino-β-carboxymuconic acid semialdehyde decarboxylase (ACMSD), which are useful for the prevention and/or the treatment of diseases and disorders associated with defects in NAD+ biosynthesis, e.g., metabolic disorders, neurodegenerative diseases, chronic inflammatory diseases, kidney diseases, and diseases associated with ageing. The present application also discloses pharmaceutical compositions comprising said compounds and the use of such compounds as a medicament.
