83611-34-1

Basic information

• Product Name: 2-Butenoic acid, 4-(2-formylphenoxy)-, ethyl ester
• CAS NO: 83611-34-1
• Molecular Formula: C13H14O4
• Molecular Weight: 234.252
• Mol File: 83611-34-1.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: 2-Butenoic acid, 4-(2-formylphenoxy)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butenoic acid, 4-(2-formylphenoxy)-, ethyl ester(83611-34-1)
• EPA Substance Registry System: 2-Butenoic acid, 4-(2-formylphenoxy)-, ethyl ester(83611-34-1)

Safety Data

• Hazardous Substances Data: 83611-34-1(Hazardous Substances Data)

Upstream product

• 28752-82-1 2-(allyloxy)benzaldehyde 
• 140-88-5 ethyl acrylate 
• 90-02-8 salicylaldehyde 
• 6065-32-3 4-bromocrotonic ethyl ester 
• 37746-78-4 4-bromo-trans-crotonic acid ethyl ester 
• 89-95-2 2-methyl-benzyl alcohol 

Downstream Products

• 1227294-10-1 (2S,3S,3aS,9bS)-3-ethyl-2-methyl-2-(4-methoxyphenyl)-1,2,3,3a,4,9b-hexahydrochromeno[4,3-b]pyrrole-2,3-dicarboxylate 
• 1227294-08-7 (2S,3S,3aS,9bS)-3-ethyl-2-methyl-2-(3-fluorophenyl)-1,2,3,3a,4,9b-hexahydrochromeno[4,3-b]pyrrole-2,3-dicarboxylate 
• 1227294-09-8 (2S,3S,3aS,9bS)-3-ethyl-2-methyl-2-(4-fluorophenyl)-1,2,3,3a,4,9b-hexahydrochromeno[4,3-b]pyrrole-2,3-dicarboxylate 
• 1227294-04-3 (2S,3S,3aS,9bS)-3-ethyl-2-methyl-2-(4-chlorophenyl)-1,2,3,3a,4,9b-hexahydrochromeno[4,3-b]pyrrole-2,3-dicarboxylate 
• 1227294-06-5 (2S,3S,3aS,9bS)-3-ethyl-2-methyl-2-(2-fluorophenyl)-1,2,3,3a,4,9b-hexahydrochromeno[4,3-b]pyrrole-2,3-dicarboxylate 
• 1227294-00-9 (2S,3S,3aS,9bS)-3-ethyl-2-methyl-2-(2-chlorophenyl)-1,2,3,3a,4,9b-hexahydrochromeno[4,3-b]pyrrole-2,3-dicarboxylate 
• 1227294-02-1 (2S,3S,3aS,9bS)-3-ethyl-2-methyl-2-(3-chlorophenyl)-1,2,3,3a,4,9b-hexahydrochromeno[4,3-b]pyrrole-2,3-dicarboxylate 
• 1227293-99-3 (2S,3S,3aS,9bS)-3-ethyl-2-methyl-2-phenyl-1,2,3,3a,4,9b-hexahydrochromeno[4,3-b]pyrrole-2,3-dicarboxylate 
• 83611-80-7 [4-(Phenyl-hydrazono)-chroman-3-yl]-acetic acid ethyl ester 

Relevant articles and documents

SUBSTITUTED CHROMANES, ANALOGS THEREOF, AND METHODS OF USE AND SYNTHESIS

Disclosed are chromane compounds, analogs thereof, and methods of their synthesis and use. The compounds may be synthesized by methods involving reductive annulations of arylidene malonates with unsaturated electrophiles using photoredox/Lewis acid cooperative catalysis. The compounds may be formulated in a pharmaceutical composition for treating one of the aforementioned diseases or disorders.

Intramolecular Stereoselective Stetter Reaction Catalyzed by Benzaldehyde Lyase

The reliable design and prediction of enzyme promiscuity to access transformations not observed in nature remains a long-standing challenge. Herein, we present the first example of an intramolecular stereoselective Stetter reaction catalyzed by benzaldehyde lyase, guided by the rational structure screening of various ThDP-dependent enzymes using molecular dynamics (MD) simulations. After optimization, high productivity (up to 99 %) and stereoselectivity (up to 99:1 e.r.) for this novel enzyme function was achieved.

Intramolecular Tandem Seleno-Michael/Aldol Reaction: A Simple Route to Hydroxy Cyclo-1-ene-1-carboxylate Esters

Intramolecular tandem seleno-Michael/aldol reaction followed by an oxidation-elimination process can be an efficient tool for the construction of hydroxy cyclo-1-ene-1-carboxylate esters from oxo-α,β-unsaturated esters. Generation of lithium selenolate from elemental selenium and n-BuLi provides a simple and efficient one-pot access to cyclic endo-Morita-Baylis-Hillman adducts.