83624-74-2

Basic information

• Product Name: Cyclohexanecarboxylic acid, 3-(4-chlorobenzoyl)-4-(4-chlorophenyl)-1-cyano-4-hydroxy-2,6-diphenyl-, ethyl ester
• CAS NO: 83624-74-2
• Molecular Formula: C35H29Cl2NO4
• Molecular Weight: 598.526
• Mol File: 83624-74-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Cyclohexanecarboxylic acid, 3-(4-chlorobenzoyl)-4-(4-chlorophenyl)-1-cyano-4-hydroxy-2,6-diphenyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanecarboxylic acid, 3-(4-chlorobenzoyl)-4-(4-chlorophenyl)-1-cyano-4-hydroxy-2,6-diphenyl-, ethyl ester(83624-74-2)
• EPA Substance Registry System: Cyclohexanecarboxylic acid, 3-(4-chlorobenzoyl)-4-(4-chlorophenyl)-1-cyano-4-hydroxy-2,6-diphenyl-, ethyl ester(83624-74-2)

Safety Data

• Hazardous Substances Data: 83624-74-2(Hazardous Substances Data)

Upstream product

• 22966-22-9 (E)-1-(4-chlorophenyl)-3-phenyl-2-propen-1-one 
• 105-56-6 ethyl 2-cyanoacetate 
• 135885-89-1 ethyl 5-(4-chlorophenyl)-2-cyano-5-oxo-3-phenylpentanoate 

Downstream Products

• 22966-22-9 (E)-1-(4-chlorophenyl)-3-phenyl-2-propen-1-one 
• 105-56-6 ethyl 2-cyanoacetate 

Relevant articles and documents

Reactivity of Some Cyclohexanol Derivatives towards Sodium Ethoxide in Ethanol

Two series of 2-(p-aroyl)-1,3,5-tri (p-aryl)-4-carbethoxy-4-cyanocyclohexan-1-ols IIa-f and IIg-h were prepared and the structure of the new compounds IIf,g,i was established by elemental analysis and spectroscopic methods. These cyclohexanol derivatives IIa-f and IIg-k were allowed to react with sodium ethoxide in absolute ethanol afforded the corresponding trans-1,3-di-(p-aryl)-2-propenones Ia-f and Ig-k, respectively besides ethyl cyanoacetate as a bi-product. The reaction kinetics has been studied spectrophotometrically at three different temperatures and the observed rate constants were calculated. Cood Hammett correlations with ρ values of series IIa-f ranged between 0.76 and 1.34, whereas of series IIg-k they were between 1.01 and 1.54 which suggest a carbanionic character of the transition states. The values of thermodynamic parameters ΔH(act.) and ΔS(act.) confirmed the proposed multi-step mechanism.