83642-29-9

Basic information

• Product Name: 1,2-dichloro-4-[4-(phenylsulfonyl)phenoxy]benzene
• Synonyms: 4-(3,4-dichlorophenoxy)phenyl phenyl sulfone; benzene, 1-(3,4-dichlorophenoxy)-4-(phenylsulfonyl)-; Benzene, 1,2-dichloro-4-(4-(phenylsulfonyl)phenoxy)-; Benzene, 1,2-dichloro-4-[4-(phenylsulfonyl)phenoxy]-
• CAS NO: 83642-29-9
• Molecular Formula: C₁₈H₁₂Cl₂O₃S
• Molecular Weight: 379.2571
• Mol File: 83642-29-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 522°C at 760 mmHg
• Flash Point: 269.5°C
• Density: 1.392g/cm³
• Vapor Pressure: 1.8E-10mmHg at 25°C
• Refractive Index: 1.625
• CAS DataBase Reference: 1,2-dichloro-4-[4-(phenylsulfonyl)phenoxy]benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-dichloro-4-[4-(phenylsulfonyl)phenoxy]benzene(83642-29-9)
• EPA Substance Registry System: 1,2-dichloro-4-[4-(phenylsulfonyl)phenoxy]benzene(83642-29-9)

Safety Data

• Hazardous Substances Data: 83642-29-9(Hazardous Substances Data)

Usage

Appearance

White solid

Solubility

Insoluble in water, soluble in organic solvents

Uses

a. Intermediate in the synthesis of pharmaceuticals and agrochemicals
b. Building block in the production of polymers and other specialty chemicals

Chemical groups

a. Dichloro (Cl2) potential for various chemical reactions and transformations
b. Phenylsulfonyl (PhSO2) contributes to the compound's versatility in organic synthesis

Safety precautions

Handle with caution, as it can be harmful if it comes into contact with the skin or if inhaled.

Upstream product

• 95-77-2 3,4-dichlorophenol 
• 312-31-2 4-(phenylsulfonyl)fluorobenzene 

Relevant articles and documents

Sulfur-substituted diphenyl ethers having antiviral activity

Novel compounds exhibiting antiviral activity are disclosed, such compounds are represented by the formula: STR1 wherein m represents the integer 0, 1 or 2; R represents trihalomethyl, alkyl or phenyl; R1 represents hydrogen, bromo, chloro, fluoro, cyano, nitro, amino, alkyl, alkoxy or trifluoromethyl; R2 represents hydroxyl, bromo, chloro, fluoro, cyano, acetyl, benzoyl, substituted benzoyl, alkyl, alkoxy, substituted alkoxy, benzyl, substituted benzyl, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylaminosulfonyl, dialkylaminosulfonyl, or the radical --O(CH2)n R4 wherein n represents the integer 1, 2 or 3 and R4 represents cyano or dialkylamino; R3 represents hydrogen, hydroxyl, bromo, chloro, fluoro, cyano, acetyl, benzoyl, substituted benzoyl, alkyl, alkoxy, substituted alkoxy, benzyl, substituted benzyl, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylaminosulfonyl, dialkylaminosulfonyl, or the radical --O(CH2)n R4 wherein n represents the integer 1, 2 or 3; and R4 represents cyano or dialkylamino; or alternatively R2 and R3 taken together represent the radical --O--C(X)2 --O-- wherein X represents hydrogen, bromo, chloro or fluoro. Methods of using the above-noted compounds and structurally related compounds to employ their antiviral activity are also disclosed as well as pharmaceutically-acceptable compositions.