83654-15-3

Basic information

• Product Name: (1E)-pent-1-en-4-yne-1,5-diyldibenzene-4,1,2-triyl tetraacetate
• Synonyms: 1,2-Benzenediol, 4,4'-((1E)-1-penten-4-yne-1,5-diyl)bis-, tetraacetate
• CAS NO: 83654-15-3
• Molecular Formula: C₂₅H₂₂O₈
• Molecular Weight: 450.4374
• Mol File: 83654-15-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 618.1°C at 760 mmHg
• Flash Point: 265.5°C
• Density: 1.29g/cm³
• Vapor Pressure: 3.3E-15mmHg at 25°C
• Refractive Index: 1.586
• CAS DataBase Reference: (1E)-pent-1-en-4-yne-1,5-diyldibenzene-4,1,2-triyl tetraacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (1E)-pent-1-en-4-yne-1,5-diyldibenzene-4,1,2-triyl tetraacetate(83654-15-3)
• EPA Substance Registry System: (1E)-pent-1-en-4-yne-1,5-diyldibenzene-4,1,2-triyl tetraacetate(83654-15-3)

Safety Data

• Hazardous Substances Data: 83654-15-3(Hazardous Substances Data)

Usage

Description

(1E)-pent-1-en-4-yne-1,5-diyldibenzene-4,1,2-triyl tetraacetate is a complex organic compound characterized by its unique and specific chemical structure. It features benzene rings and acetyl groups, and is synthesized through the reaction of pent-1-en-4-yne-1,5-diol and benzene-1,4-diboronic acid with acetic anhydride. As a tetraacetate, this compound has four acetyl groups attached to its main structure, suggesting potential applications in various fields of organic chemistry, including organic synthesis, pharmaceuticals, and materials science. However, further research and testing are required to fully explore and understand its capabilities and uses.

Uses

Used in Organic Synthesis:
(1E)-pent-1-en-4-yne-1,5-diyldibenzene-4,1,2-triyl tetraacetate is used as a key intermediate in organic synthesis for the creation of various complex organic molecules. Its unique structure allows for multiple points of chemical modification, making it a versatile building block for the development of new compounds with specific properties.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (1E)-pent-1-en-4-yne-1,5-diyldibenzene-4,1,2-triyl tetraacetate is used as a precursor for the synthesis of potential drug candidates. Its structural features may contribute to the development of new therapeutic agents with novel mechanisms of action, targeting a range of diseases and conditions.
Used in Materials Science:
(1E)-pent-1-en-4-yne-1,5-diyldibenzene-4,1,2-triyl tetraacetate is utilized in materials science for the development of advanced materials with specific properties. Its incorporation into polymers or other materials can lead to the creation of new materials with improved characteristics, such as enhanced stability, reactivity, or selectivity, depending on the intended application.

Upstream product

• 108-24-7 acetic anhydride 
• 83644-00-2 (E)-1,5-bis(3',4'-dihydroxyphenyl)pent-4-en-1-yne 
• 83643-94-1 (E)-1,5-bis-(4'-β-D-glucopyranosyloxy-3'-hydroxyphenyl)pent-1-en-4-yne 

Relevant articles and documents

Inhibitory effect of di-catechol rooperol on VCAM-1 and iNOS expression in cytokine-stimulated endothelium

Induced expression of vascular cell adhesion molecule-1 (VCAM-1) and of nitric oxide synthase (iNOS) is believed to play a role in the pathogenesis of atherosclerosis, asthma, as well as other inflammatory disorders. In the current study we examined the effect of the di-catechol rooperol [(E)-1,5-bis (3',4'-dihydroxyphenyl) pent-4-en-1-yne] on the process of microvascular endothelial cell (MME) activation by TNF-α and IFN-γ. We show that rooperol decreases VCAM-1 and iNOS mRNA levels in cytokine-activated MME with subsequent inhibition of VCAM-1 membrane expression as measured by adhesion of P815 cells to MME monolayers, and NO production, as reflected in the nitrite concentration in culture medium. The properties of rooperol now described suggest that rooperol may be an anti-inflammatory agent useful in the treatment of several inflammatory disorders.