83674-71-9 Usage
Description
2,4-Diiodopyridine is an organic compound characterized by the presence of two iodine atoms at the 2nd and 4th positions on the pyridine ring. It is a versatile intermediate in organic synthesis and has potential applications in various fields due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
2,4-Diiodopyridine is used as a synthetic intermediate for the production of nicotelline-d8 (N401202). Nicotelline is a biomarker and environmental tracer for tobacco smoke, and its isotope-labelled form serves as a nicotine-related metabolite with potential as an inhibitor of human cytochrome P-450 2A6. This makes 2,4-Diiodopyridine an essential component in the development of drugs and therapies targeting nicotine addiction and tobacco-related health issues.
Check Digit Verification of cas no
The CAS Registry Mumber 83674-71-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,6,7 and 4 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 83674-71:
(7*8)+(6*3)+(5*6)+(4*7)+(3*4)+(2*7)+(1*1)=159
159 % 10 = 9
So 83674-71-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H3I2N/c6-4-1-2-8-5(7)3-4/h1-3H
83674-71-9Relevant articles and documents
SUBSTITUTED TRIAZOLES AND THEIR USE FOR TREATMENT AND/OR PREVENTION NEUROLOGICAL AND PSYCHIATRIC DISORDERS
-
Page/Page column 53, (2013/07/31)
This invention relates to compounds of formula (I), their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. A, B, Ar, R1, R2, R3 have meanings given in the description.
Iodopyridines from bromo- and chloropyridines
Corcoran,Bang
, p. 6757 - 6758 (2007/10/02)
Bromo- and chloropyridines may be converted to the corresponding iodopyridines by treatment with sodium iodide and acetyl chloride in acetonitrile.