83692-82-4 Usage
Description
NITRO-GLU-P-1 is a highly mutagenic metabolite of 2-Amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole (A616100). It is a chemical compound that has the potential to cause mutations in DNA, which can lead to various health issues and diseases.
Uses
NITRO-GLU-P-1 is used as a mutagenic agent in research and development for understanding the mechanisms of DNA mutations and their effects on cellular processes. It can be employed in various applications, such as:
Used in Pharmaceutical Research:
NITRO-GLU-P-1 is used as a mutagenic agent for studying the effects of DNA mutations on the development and progression of various diseases, including cancer. It can help researchers identify potential therapeutic targets and develop new drugs to treat these conditions.
Used in Environmental Studies:
NITRO-GLU-P-1 can be used as a mutagenic agent in environmental studies to assess the impact of pollutants and other environmental factors on DNA stability and genetic mutations. This can help in understanding the role of environmental factors in the development of various diseases and disorders.
Used in Genetic Engineering:
NITRO-GLU-P-1 can be employed as a mutagenic agent in genetic engineering to create genetically modified organisms with desired traits. It can be used to induce mutations in specific genes, leading to the development of new varieties of plants, animals, or microorganisms with improved characteristics.
Check Digit Verification of cas no
The CAS Registry Mumber 83692-82-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,6,9 and 2 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 83692-82:
(7*8)+(6*3)+(5*6)+(4*9)+(3*2)+(2*8)+(1*2)=164
164 % 10 = 4
So 83692-82-4 is a valid CAS Registry Number.
83692-82-4Relevant articles and documents
Modification of DNA with Potent Mutacarcinogenic 2-Amino-6-methyldipyridoimidazole Isolated from a Glutamic Acid Pyrolysate: Structure of the Modified Nucleic Acid Base and Initial Chemical Event Caused by the Mutagen
Hashimoto, Yuichi,Shudo, Koichi,Okamoto, Toshihiko
, p. 7636 - 7640 (1982)
2-Amino-6-methyldipyridoimidazole (Glu-P-1), a potent mutacarcinogen isolated from a glutamic acid pyrolysate, reacted with DNA in vitro and in vivo.The structure of the modified nucleic acid base was determined as 2-(8-guanylylamino)-6-met
