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83705-13-9

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83705-13-9 Usage

General Description

Selenazofurin is a synthetic chemical compound that belongs to the class of nucleoside analogs. It is a potent and selective inhibitor of the enzyme inosine monophosphate dehydrogenase (IMPDH), which is involved in the de novo synthesis of guanosine nucleotides. Selenazofurin has been found to exhibit anti-proliferative and anti-tumor effects in various cancer cell lines by disrupting the biosynthesis of guanine nucleotides, which are essential for DNA and RNA synthesis. Selenazofurin has shown potential as a therapeutic agent for the treatment of certain types of cancer, particularly those with elevated levels of IMPDH activity. Additionally, its specificity for IMPDH makes it a promising tool for studying the role of guanine nucleotide biosynthesis in various biological processes. Further research is ongoing to explore the potential of selenazofurin in clinical settings.

Check Digit Verification of cas no

The CAS Registry Mumber 83705-13-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,7,0 and 5 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 83705-13:
(7*8)+(6*3)+(5*7)+(4*0)+(3*5)+(2*1)+(1*3)=129
129 % 10 = 9
So 83705-13-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H12N2O5Se/c10-8(15)3-2-17-9(11-3)7-6(14)5(13)4(1-12)16-7/h2,4-7,12-14H,1H2,(H2,10,15)

83705-13-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-selenazole-4-carboxamide

1.2 Other means of identification

Product number -
Other names Selenazofurin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:83705-13-9 SDS

83705-13-9Downstream Products

83705-13-9Relevant articles and documents

A synthesis of 2-β-D-ribofuranosyl-4-selenazolecarboxamide (selenazofurin) and certain N-substituted amide derivatives suitable for large scale syntheses

Cook,McNamara

, p. 155 - 160 (1986)

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