83712-60-1 Usage
Description
Defibrotide is an antithrombotic, partially-depolymerized polydeoxyribonucleotide derived from bovine lungs. It is known for its potential in treating various conditions, including myocardial and severe lower limb ischemia, renal failure due to thrombotic microangiopathy, thrombophlebitis, and as a prophylactic for deep vein thrombosis, possibly through the stimulation of PCI2.
Uses
Used in Cardiovascular Applications:
Defibrotide is used as an antithrombotic agent for the treatment of myocardial and severe lower limb ischemia. It helps improve blood flow and reduce the risk of blood clot formation in these areas.
Used in Renal Applications:
Defibrotide is used as a therapeutic agent for renal failure due to thrombotic microangiopathy. It aids in mitigating the damage caused by the condition and supports the recovery of kidney function.
Used in Vascular Applications:
Defibrotide is used as a treatment for thrombophlebitis, an inflammation of a vein usually caused by a blood clot. It helps in reducing inflammation and preventing further clot formation.
Used in Prophylactic Applications:
Defibrotide is used as a prophylactic agent for the prevention of deep vein thrombosis. It helps in maintaining proper blood flow and reducing the risk of clot formation in the deep veins.
Brand names: Noravid and Prociclide.
Originator
Crinos (Italy)
Check Digit Verification of cas no
The CAS Registry Mumber 83712-60-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,7,1 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 83712-60:
(7*8)+(6*3)+(5*7)+(4*1)+(3*2)+(2*6)+(1*0)=131
131 % 10 = 1
So 83712-60-1 is a valid CAS Registry Number.