83716-63-6

Basic information

• Product Name: 2-Azetidinone, 4-(2-chlorophenyl)-
• Synonyms: 4-(2-Chlorophenyl)-2-azetidinone;4-(2-Chloro-phenyl)-azetidin-2-one
• CAS NO: 83716-63-6
• Molecular Formula: C9H8ClNO
• Molecular Weight: 181.622
• Mol File: 83716-63-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Azetidinone, 4-(2-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Azetidinone, 4-(2-chlorophenyl)-(83716-63-6)
• EPA Substance Registry System: 2-Azetidinone, 4-(2-chlorophenyl)-(83716-63-6)

Safety Data

• Hazardous Substances Data: 83716-63-6(Hazardous Substances Data)

Usage

Commonly known as

4-(2-chlorophenyl)-2-azetidinone

Use

Synthesis of pharmaceuticals and agrochemicals

Type

Lactam (cyclic amide)

Properties

Antibacterial and antifungal

Potential uses

Treatment of various diseases, including cancer

Common applications

Research and development laboratories

Availability

Not commonly found in commercial products for general public use

Upstream product

• 1189-71-5 isocyanate de chlorosulfonyle 
• 2039-87-4 2-chlorostyrene 
• 566198-10-5 (+/-)-trimethylsilyl β-(N-trimethylsilylamino)-β-(2-chlorophenyl)propionate 
• 68208-20-8 3-amino-3-(2-chloro-phenyl)-propionic acid 
• 89-98-5 2-chloro-benzaldehyde 

Downstream Products

• 1407189-14-3 N-(benzyl)-4-(2-chlorophenyl)-azetidin-2-one 
• 57152-94-0 N-benzylcinnamamide 
• 930769-47-4 (S)-4-(2-chlorophenyl)-2-azetidinone 
• 948027-10-9 C₉H₈ClNO 
• 1372804-79-9 3-amino-3-(2-chlorophenyl)-1-phenylpropan-1-one 
• 1331772-10-1 C₁₃H₁₄ClNO₂ 
• 740794-79-0 (R)-3-amino-3-(2-chlorophenyl)propionic acid 

Relevant articles and documents

The acid-mediated ring opening reactions of α-aryl-lactams

4-Aryl-azetidin-2-ones (β-lactams) undergo ring opening with triflic acid to give cinnamamides which, in benzene, react further to give 3-aryl-3-phenyl-propionamides. Prolonged reaction times in benzene give 3,3-diphenyl-propionamide via an aryl/phenyl ex

Electron Impact Induced Fragmentation of Aromatic Alkoxyimines II [5]. Formation and Transformation of Heterocyclic Radical Cations in the Gas Phase

The molecular ion 1 of N-(n-propoxy)benzaldimine I rearranges by an 1,5-H-shift to the δ-distonic ion 2 which subsequently cyclizes to the α-distonic ion 3. Homolytic cleavage of the N-O bond in 3 results in the δ-distonic ion 4 which expels CH2/sub