837368-26-0

Basic information

• Product Name: Benzaldehyde, 2,3,5,6-tetrafluoro-4-iodo-
• CAS NO: 837368-26-0
• Molecular Formula: C7HF4IO
• Molecular Weight: 303.982
• Mol File: 837368-26-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 2,3,5,6-tetrafluoro-4-iodo-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2,3,5,6-tetrafluoro-4-iodo-(837368-26-0)
• EPA Substance Registry System: Benzaldehyde, 2,3,5,6-tetrafluoro-4-iodo-(837368-26-0)

Safety Data

• Hazardous Substances Data: 837368-26-0(Hazardous Substances Data)

Upstream product

• 652-18-6 2,3,5,6-tetrafluorobenzoic acid 
• 528869-06-9 1,2,4,5-tetrafluoro-3-(1,3-dioxol-2-yl)benzene 
• 944-43-4 4-amino-2,3,5,6-tetrafluorobenzoic acid 
• 873536-93-7 2,3,5,6-tetrafluoro-4-iodo-benzoic acid 
• 837368-27-1 2-(2,3,5,6-tetrafluoro-4-iodo-phenyl)-[1,3]dioxolane 

Relevant articles and documents

Molecularly imprinted polymers with halogen bonding-based molecular recognition sites

Molecular recognition materials bearing halogen bonding-based binding sites were synthesized by a non-covalent imprinting technique using a 2,3,5,6-tetrafluoro-4-iodostyrene (TFIS) as the functional monomer. The binding sites were generated by co-polymeri

A convenient preparation of 2,3,5,6-tetrafluoro-4-iodo-benzaldehyde and its application in porphyrin synthesis

An efficient synthesis of 2,3,5,6-tetrafluoro-4-iodo-benzaldehyde (1) is presented. This new compound was readily obtained via iodination at low temperature of the lithio derivative of 2-(2,3,5,6-tetrafluoro-phenyl)-[1,3]dioxolane (4). The crystal structure of 1 consists of linear polymeric chains, with non-covalent O?I bonding as the directing interaction, responsible for the observed assembly. Aldehyde 1 is further employed in the synthesis of 5,10,15,20-tetrakis(pentafluorophenyl) porphyrin (6), a potential precursor of supramolecular assemblies.

Halogen Bonding Molecular Capsules

Molecular capsules based solely on the interaction of halogen bonding (XB) are presented along with their host-guest binding properties in solution. The first example of a well-defined four-point XB supramolecular system is realized by decorating resorcin[4]arene cavitands with polarized halogen atoms for dimerization with tetra(4-pyridyl) resorcin[4]arene cavitands. NMR binding data for the F, Cl, Br, and I cavitands as the XB donor show association constants (Ka) of up to 5370 M-1 (ΔG283 K=-4.85 kcal mol-1, for I), even in XB-competitive solvent, such as deuterated benzene/acetone/methanol (70:30:1) at 283 K, where comparable monodentate model systems show no association. The XB capsular geometry is evidenced by two-dimensional HOESY NMR, and the thermodynamic profile shows that capsule formation is enthalpically driven. Either 1,4-dioxane or 1,4-dithiane are encapsulated within each of the two separate cavities within the XB capsule, with of up to Ka=9.0 108 M-2 (ΔG283 K=-11.6 kcal mol-1).