83759-00-6

Basic information

• Product Name: Benzoyl chloride, 3,4-dihydroxy- (9CI)
• Synonyms: Benzoyl chloride, 3,4-dihydroxy- (9CI);Benzoyl chloride, 3,4-dihydroxy-
• CAS NO: 83759-00-6
• Molecular Formula: C₇H₅ClO₃
• Molecular Weight: 172.5658
• Product Categories: ACIDHALIDE
• Mol File: 83759-00-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 352.5±32.0 °C(Predicted)
• Appearance: /
• Density: 1.531±0.06 g/cm3(Predicted)
• PKA: 7.17±0.18(Predicted)
• CAS DataBase Reference: Benzoyl chloride, 3,4-dihydroxy- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl chloride, 3,4-dihydroxy- (9CI)(83759-00-6)
• EPA Substance Registry System: Benzoyl chloride, 3,4-dihydroxy- (9CI)(83759-00-6)

Safety Data

• Hazardous Substances Data: 83759-00-6(Hazardous Substances Data)

Upstream product

• 99-50-3 3,4-Dihydroxybenzoic acid 

Downstream Products

• 132640-17-6 N-(3,5-dicarboxy)phenyl-3,4-di-hydroxybenzamide 
• 99499-10-2 3,4-Dihydroxy-N-isobutyl-benzamide 
• 1616086-49-7 4-(5-phenyl-1,3,4-oxadiazole-2yl)benzene-1,2-diol 

Relevant articles and documents

Electrochemically stimulated molecule release associated with interfacial pH changes

A new linker with a hydrolyzable aryl ester bond was used for electrode modification. Basic pH locally produced at the electrode surface upon electrochemical reduction of O2 resulted in the hydrolytic cleavage of the aryl ester bond and release of the immobilized fluorescent dye used as a model compound.

Synthesis, protolytic equilibria, and antimicrobial action of nifuroxazide analogs

The present paper reports on the synthesis of four hydrazones derived from 5-nitro-2-furfural, 5-nitro-2-thiophenal, isoniazid, 2,4- and 3,4-dihydroxy-N′-methylenebenzohydrazide. The acid-base dissociation constants of these compounds were determined in an aqueous solution. The protolytic equilibria-related ability of hydrazones to “sense” anions in dimethyl sulfoxide-containing water of different concentrations is studied using spectrophotometry, NMR spectroscopy, and quantum chemistry methods. The antimicrobial action of the hydrazones was tested and compared with that of the known drug nifuroxazide.

Synthesis and antioxidant activity of 1,3,4-oxadiazoles and their diacylhydrazine precursors derived from phenolic acids

Eight 1,3,4-oxadiazole derivatives containing phenolic acid moieties (7a-h) and eight of their diacylhydrazine precursors (6a-h) were synthesized, characterized using spectroscopic methods and examined by scavenging of stable DPPH (2,2-diphenyl-1-picrylhydrazyl) radicals. The most potent phenolic 1,3,4-oxadiazoles showed better DPPH scavenging activity in comparison with their corresponding diacylhydrazine precursors as a result of participation of both aromatic rings and a 1,3,4-oxadiazole moiety in resonance stabilization of the formed phenoxyl radical. Four diacylhydrazines (6d, 6e, 6g, and 6h) and four 1,3,4-oxadiazoles (7d, 7e, 7g and 7h) with the best DPPH scavenging activity, were chosen for further evaluation of their antioxidant potential through various assays. The investigated compounds exerted pronounced ABTS radical scavenging capacity, moderate to good H2O2 scavenging properties and strong ferric ion reducing capacity. Further in vitro evaluation of the antioxidant properties of the most active compounds demonstrated their protective effects in normal lung fibroblasts MRC-5 against hydrogen peroxide induced oxidative stress. Diacylhydrazine 6h increased two times the activity of glutathione peroxidase in treated cells in comparison with a control sample and did not affect the superoxide dismutase activity.