838-21-1

Basic information

• Product Name: (4-BroMophenyl)(4-Methoxyphenyl)Methanol
• Synonyms: (4-BroMophenyl)(4-Methoxyphenyl)Methanol
• CAS NO: 838-21-1
• Molecular Formula: C₁₄H₁₃BrO₂
• Molecular Weight: 293.15582
• Mol File: 838-21-1.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (4-BroMophenyl)(4-Methoxyphenyl)Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (4-BroMophenyl)(4-Methoxyphenyl)Methanol(838-21-1)
• EPA Substance Registry System: (4-BroMophenyl)(4-Methoxyphenyl)Methanol(838-21-1)

Safety Data

• Hazardous Substances Data: 838-21-1(Hazardous Substances Data)

Usage

Description

(4-Bromophenyl)(4-Methoxyphenyl)Methanol is a chemical compound that belongs to the class of arylalkyl alcohols. It is a white solid with a molecular formula of C14H13BrO2 and a molecular weight of 277.16 g/mol. (4-BroMophenyl)(4-Methoxyphenyl)Methanol is characterized by the presence of both bromo and methoxy functional groups, which make it valuable for creating molecules with specific properties and activities.

Uses

Used in Pharmaceutical Industry:
(4-Bromophenyl)(4-Methoxyphenyl)Methanol is used as a building block for the synthesis of various pharmaceuticals. Its unique functional groups allow for the development of molecules with targeted properties and activities, contributing to the creation of new drugs with potential therapeutic applications.
Used in Organic Compounds Synthesis:
In the field of organic chemistry, (4-Bromophenyl)(4-Methoxyphenyl)Methanol serves as a versatile intermediate. Its bromo and methoxy groups facilitate the synthesis of a wide range of organic compounds, expanding the possibilities for chemical research and development.
Used in Agrochemical Development:
(4-Bromophenyl)(4-Methoxyphenyl)Methanol is also utilized in the development of new agrochemicals. Its functional groups enable the synthesis of molecules with specific activities, potentially leading to the creation of more effective and targeted pesticides or other agricultural products.
Used in Material Science:
(4-BroMophenyl)(4-Methoxyphenyl)Methanol finds applications in material science as well. The unique properties conferred by its functional groups can be harnessed to develop new materials with specific characteristics, such as improved stability, reactivity, or other desirable traits.

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 
• 1122-91-4 4-bromo-benzaldehyde 
• 5467-74-3 4-Bromophenylboronic acid 
• 123-11-5 4-methoxy-benzaldehyde 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 106-37-6 1.4-dibromobenzene 
• 7294-51-1 2,4,6-tris(4-methoxyphenyl)boroxine 
• 100-66-3 methoxybenzene 

Downstream Products

• 874126-49-5 C₁₇H₁₅BrO₂ 
• 874126-52-0 4-{3-[(4-bromo-phenyl)-(4-methoxy-phenyl)-methoxy]-prop-1-ynyl}-benzaldehyde 
• 874126-55-3 (4-{3-[(4-bromo-phenyl)-(4-methoxy-phenyl)-methoxy]-prop-1-ynyl}-phenyl)-(4-methoxy-phenyl)-methanol 
• 874126-57-5 C₃₄H₂₉BrO₄ 
• 54118-75-1 4-bromo-4'-methoxybenzophenone 

Relevant articles and documents

Dirhodium-Catalyzed Enantioselective B?H Bond Insertion of gem-Diaryl Carbenes: Efficient Access to gem-Diarylmethine Boranes

The scarcity of reliable methods for synthesizing chiral gem-diarylmethine borons limits their applications. Herein, we report a method for highly enantioselective dirhodium-catalyzed B?H bond insertion reactions with diaryl diazomethanes as carbene precursors. These reactions afforded chiral gem-diarylmethine borane compounds in high yield (up to 99 % yield), high activity (turnover numbers up to 14 300), high enantioselectivity (up to 99 % ee) and showed unprecedented broad functional group tolerance. The borane compounds synthesized by this method could be efficiently transformed into diaryl methanol, diaryl methyl amine, and triaryl methane derivatives with good stereospecificity. Mechanistic studies suggested that the borane adduct coordinated to the rhodium catalyst and thus interfered with decomposition of the diazomethane, and that insertion of a rhodium carbene (generated from the diaryl diazomethane) into the B?H bond was most likely the rate-determining step.

A nontransmetalation reaction pathway for anionic four-electron donor-based palladacycle-catalyzed addition reactions of arylborons with aldehydes

A nontransmetalation reaction pathway for anionic four-electron donor-based (Type I) palladacycle-catalyzed addition reactions of arylborons with aldehydes is described. This new reaction pathway offers new catalysis opportunities for Type I palladacycle-catalyzed addition reactions such as the exceptionally low catalyst loading catalysis, with the catalyst loading as low as 0.0005 mol %. This new pathway may be applicable for other transition metal-catalyzed addition reactions and might lead to the development of new reactions including sequential/tandem reactions.

Synthesis and characterization of low generation halogenated linear poly(arylpropargyl)ether (PAPE) branches via selective palladium catalyzed coupling reactions

A rapid convergent synthesis of first- and second-generation halogenated linear poly(arylpropargyl ether) branches 7 and 10 is described. The key step of the sequence studied involves a selective Sonogashira-Linstrumelle (S-L) cross-coupling reaction of a