83808-21-3 Usage
Derived from
Piperazine
Type of compound
Chemical compound
Usage
Building block in the synthesis of pharmaceuticals and other organic compounds
Substitution
4-methyl
Impact of substitution
Imparts unique chemical and biological properties
Potential applications
Pharmaceutical industry and organic synthesis
Additional research needed
Yes
Check Digit Verification of cas no
The CAS Registry Mumber 83808-21-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,8,0 and 8 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 83808-21:
(7*8)+(6*3)+(5*8)+(4*0)+(3*8)+(2*2)+(1*1)=143
143 % 10 = 3
So 83808-21-3 is a valid CAS Registry Number.
83808-21-3Relevant articles and documents
Conformationally restricted thiazole derivatives as novel class of 5-HT3 receptor ligands
Perrone,Berardi,Colabufo,Tortorella,Lograno,Daniele,Govoni
, p. 77 - 82 (2007/10/02)
A new series of tricyclic derivatives of 2-methyl-naphtho[1,2-d] thiazole were synthesized in order to investigate the effects of the conformational restriction of bicyclic thiazole derivatives previously reported on the 5-HT3 receptor affinity. The basic moiety in these compounds is represented by the terminal nitrogen of N-methyl-piperazine or N-methyl-piperidine ring-linked at 2-methyl. All the tricyclic derivatives have a significant 5-HT3 receptor binding affinity and the terminal piperazine ring is more suitable than piperidine one.