83831-38-3Relevant articles and documents
SOME DEVELOPMENTS IN THE PHOSPHITE-TRIESTER METHOD FOR SYNTHESIS OF OLIGONUCLEOTIDES
Letsinger, R. L.,Groody, E. P.,Lander, N.,Tanaka, T.
, p. 137 - 144 (2007/10/02)
1,1-Dimethyl-2,2,2-trichloroethyl has merit as a protecting group for P-O in the phosphite-triester synthesis of oligonucleotides.Use of this group enables one to simplify procedures for preparing active nucleoside phosphorochloridite reagents, to remove