83866-23-3Relevant articles and documents
SOME 1-β-D-RIBOFURANOSYL-5-PHENYLCYTOSINES AND -5-(2-CHLOROPHENYL)-2-THIOCYTOSINE
Budesinsky, Zdenek,Smejkal, Frantisek,Budesinsky, Milos
, p. 2145 - 2149 (2007/10/02)
5-Phenylcytidine (XI), 5-(4-nitrophenyl)cytidine (XII) and 5-(2-chlorophenyl)-2-thiocytidine (XIII) were prepared from corresponding trimethylsilyl derivatives V-VII.Nitro derivative XII was converted to amino derivative XIV by catalytic reduction.Cytidines XI-XIV and the starting cytosines I-IV do not display any in vitro inhibitory effect against the influenza virus AWS, virus NDV, vaccinia, herpes simplex and WEE, or in vivo effect on mice infected with the herpes simplex virus type 2 (HSV-2) either.