83935-54-0Relevant articles and documents
ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF
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Paragraph 00359, (2016/04/20)
Described herein are compounds of Formula (S-I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting arginine methyltransferase activity. Methods of using the compounds for treating arginine methyltransferase-mediated disorders are also described.
Stereocontrolled total synthesis of (±)-FR901483
Ieda, Shigeru,Asoh, Yusuke,Fujimoto, Teppei,Kitaoka, Haruka,Kan, Toshiyuki,Fukuyama, Tohru
experimental part, p. 721 - 738 (2009/12/26)
The total synthesis of potent immunosuppressant FR901483 (1) is reported. The remarkable feature of our convergent synthesis is the p-methoxybenzyl and methylamino groups are stereoselectively incorporated within the tri-cyclic core skeleton. The skeleton
Phase-transfer-catalysed Preparation of N-Alkylated Trihydroxamic Acids
Hoffmann, Pascal,Doucet, Jean-Baptiste,Li, Wenhao,Vergnes, Laurent,Labidalle, Serge
, p. 218 - 219 (2007/10/03)
We describe a synthetic route involving phase transfer catalysis leading to a series of tripodal N-alkylated hydroxamic acids as models of desferrioxamine; iron(III) exchange reactions between their iron complexes and EDTA were investigated.
