83942-10-3

Basic information

• Product Name: 4,5-DICHLORO-6-METHYLPYRIMIDINE
• Synonyms: 4,5-DICHLORO-6-METHYLPYRIMIDINE
• CAS NO: 83942-10-3
• Molecular Formula: C₅H₄Cl₂N₂
• Molecular Weight: 163.01
• Product Categories: Heterocycle-Pyrimidine series
• Mol File: 83942-10-3.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 242.637ºC at 760 mmHg
• Flash Point: 123.983ºC
• Appearance: /
• Density: 1.404g/cm3
• Vapor Pressure: 0.052mmHg at 25°C
• Refractive Index: 1.551
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -0.69±0.26(Predicted)
• CAS DataBase Reference: 4,5-DICHLORO-6-METHYLPYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-DICHLORO-6-METHYLPYRIMIDINE(83942-10-3)
• EPA Substance Registry System: 4,5-DICHLORO-6-METHYLPYRIMIDINE(83942-10-3)

Safety Data

• Hazardous Substances Data: 83942-10-3(Hazardous Substances Data)

Usage

General Description

4,5-Dichloro-6-methylpyrimidine is a chemical compound belonging to the class of organic substances known as pyrimidines and pyrazines. Pyrimidines are aromatic compounds that contain a pyrimidine ring which is a six-membered heterocycle made up of two nitrogen centers and four carbon atoms. The specific structure of this compound includes two chlorine atoms and one methyl group attached to the pyrimidine ring. 4,5-Dichloro-6-methylpyrimidine is typically utilized as a chemical reagent, primarily in the field of chemistry for various synthesis processes. Its physical properties and reactivity may vary based on factors such as temperature, concentration and pressure. Like many chemicals, it should be stored safely and away from incompatible substances. Currently, there's limited information readily available on its toxicity, health impacts, or environmental effects. Hence, it's always advised to handle it with care.

InChI:InChI=1/C5H4Cl2N2/c1-3-4(6)5(7)9-2-8-3/h2H,1H3

Upstream product

• 3524-87-6 6-methyl-3H-pyrimidin-4-one 
• 7752-72-9 5-Chloro-6-hydroxy-4-methylpyrimidine 

Downstream Products

• 54198-82-2 5-chloro-4-methylpyrimidine 
• 130362-01-5 dl-5-Chloro-6-methyl-4-(α-methyl-4-difluoromethoxybenzyl-amino)pyrimidine 
• 114969-55-0 5-Chloro-4-methyl-pyrimidine 1-oxide 
• 114969-79-8 5-Chloro-4-methyl-pyrimidine-2-carbonitrile 

Relevant articles and documents

SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF

The present invention discloses a substituted pyrimidine compound. The structure is shown in general formula I. The definition of each substituent in the formula is described in the description. The compound of the present invention has broad-spectrum fungicidal, insecticidal and acaricidal activity, and has excellent control effects on cucumber downy mildew, powdery mildew, corn rust, anthrax, rice blast, aphids, Tetranychus cinnabarinus and the like.

Spirocyclic compound containing pyrimidine and application thereof

The invention discloses a pyrimidine-containing spiro compound, structure as shown in a general formula I : The compound of the invention has a broad-spectrum bactericidal activity . and has an excellent control effect, on cucumber downy mildew, wheat powdery mildew, corn rust, rice blast, cucumber anthracnose and the like.

Design, synthesis, insecticidal, and acaricidal activities of novel pyrimidinamine derivatives containing a biphenyl ether

A series of original pyrimidinamine derivatives containing a biphenyl ether moiety were designed and synthesized. Their structures were confirmed by 1H NMR, MS, and elemental analyses. Their insecticidal activities against lepidopteran and hemiptera insects and acaricidal activities were tested. The results of bioassay demonstrated that 9k showed the best activity (LC50 = 2.08 mg/L) against Tetranychus urticae, which is comparable with the positive control, spirotetramat (LC50 = 2.27 mg/L), and 9g showed better activity (LC50 = 0.52 mg/L) against Aphis fabae than the positive control, imidacloprid (LC50 = 1.02 mg/L), and relatively good activity (LC50 = 2.49 mg/L) against T urticae. Their structure-activity relationships indicated that both an ethyl group on the 4-position of the pyrimidine ring and alkyl chain as a para-substituent group of the benzene ring showed good biological activity.