839710-38-2 Usage
Description
(S)-4-Boc-3-morpholineacetic acid, also known as (S)-1-(tert-butoxycarbonyl)-3-(4-morpholinyl)propane-1-acetic acid, is a chiral compound that features a Boc-protected morpholine moiety attached to a chiral acetic acid backbone. This unique structure endows it with specific reactivity and selectivity in chemical synthesis and medicinal chemistry applications.
Uses
Used in Pharmaceutical Industry:
(S)-4-Boc-3-morpholineacetic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds for the treatment of chronic inflammatory diseases. Its Boc-protected morpholine group provides a versatile handle for further functionalization and derivatization, facilitating the development of new therapeutic agents.
Used in the Preparation of Imidazole Compounds:
(S)-4-Boc-3-morpholineacetic acid is used as a building block in the preparation of imidazole compounds, which have potential applications in the treatment of articular rheumatism, inflammatory bowel disease, and scleroderma. The chiral center in this compound ensures that the final imidazole product has the desired stereochemistry, which is crucial for biological activity and efficacy.
Check Digit Verification of cas no
The CAS Registry Mumber 839710-38-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,3,9,7,1 and 0 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 839710-38:
(8*8)+(7*3)+(6*9)+(5*7)+(4*1)+(3*0)+(2*3)+(1*8)=192
192 % 10 = 2
So 839710-38-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H19NO5/c1-11(2,3)17-10(15)12-4-5-16-7-8(12)6-9(13)14/h8H,4-7H2,1-3H3,(H,13,14)/t8-/m0/s1
839710-38-2Relevant articles and documents
SUBSTITUTED MORPHOLINES AS MODULATORS FOR THE CALCIUM SENSING RECEPTOR
-
, (2014/02/15)
Compounds of Formula (I) along with processes for their preparation that are useful for treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (CaSR) receptors. Methods of treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (CaSR) receptors of Formula (I).
Process for producing enantiopure beta-amino acid derivatives, and enantiopure beta-amino acid derivatives
-
, (2008/06/13)
Process for producing enantiopure β-amino acid derivatives corresponding to general formula (I) R1-NZ-CHR2—CH2—COOR3 (I) in which R1 and R2 independently denote organic residues optionally forming a cyclic substituent, R3 denotes H or an organic residue, and Z represents H or an amino function-protecting group, comprising a step in which a mixture of enantiomers of a compound corresponding to general formula (II) R1-NZ-CHR2—CH2—COOR4 (II) in which R1, R2 and Z are as defined for formula (I), and R4 is an organic residue, is subjected to hydrolysis in the presence of a lipase.
Enzymatic resolution of cyclic N-Boc protected β-aminoacids
Pousset, Cyrille,Callens, Roland,Haddad, Mansour,Larcheveque, Marc
, p. 3407 - 3412 (2007/10/03)
Methyl and ethyl esters of N-Boc homoproline, homopipecolic acid and 3-carboxymethyl-morpholine were kinetically resolved by hydrolysis catalysed by Burkholderia cepacia lipase to give the corresponding acids and residual esters in enantiomeric excesses better than 99% (E > 100).
