83983-03-3Relevant articles and documents
Preparation method of olaparib impurity
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Paragraph 0010; 0016, (2021/01/30)
The invention discloses a preparation method of an olaparib impurity V. The compound V provided by the invention can be used as a reference substance for detecting olaparib related substances, and isused for purity control of olaparib bulk drugs and preparations. According to the preparation method, o-formylbenzoic acid is taken as an initial raw material, the compound V is obtained through condensation, substitution, dehydration and other operations, the method is high in selectivity, mild in condition and easy to operate, and the obtained product is high in purity.
Isoquino[3,2-a]phthalazine-5,8-diones
Dusemund
, p. 925 - 930 (2007/10/02)
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