84023-71-2

Basic information

• Product Name: N-(o-hydroxybenzylidene)-2-oxotetrahydro-3-thiophenine
• Synonyms: N-(o-hydroxybenzylidene)-2-oxotetrahydro-3-thiophenine
• CAS NO: 84023-71-2
• Molecular Weight: 221.28
• Mol File: 84023-71-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(o-hydroxybenzylidene)-2-oxotetrahydro-3-thiophenine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(o-hydroxybenzylidene)-2-oxotetrahydro-3-thiophenine(84023-71-2)
• EPA Substance Registry System: N-(o-hydroxybenzylidene)-2-oxotetrahydro-3-thiophenine(84023-71-2)

Safety Data

• Hazardous Substances Data: 84023-71-2(Hazardous Substances Data)

Upstream product

• 90-02-8 salicylaldehyde 
• 10593-85-8 DL-homocysteine thiolactone 

Relevant articles and documents

Oxotetrahydrothiophenes

Biological activity is retained while reducing toxicity to animals, particularly mammals, e.g. humans, when a physiologically-active and pharmacologically-acceptable compound (having or structurally modified to have an aldehyde function) is condensed with any of the six (mono)amino(mono)oxotetrahydrothiophenes, e.g. homocysteine thiolactone, to form a Schiff Base (a 4-butyrothiolactone-2-imine or γ-thiobutyrolactone-α-imine). The invention is directed to every Schiff Base which is a condensate of a physiologically-active and pharmacologically-acceptable compound with a (mono)amino(mono)oxotetrahydrothiophene. These Schiff Bases have a unifying common property in reduced toxicity, while maintaining the biological properties "carried" by the imine substituents. They concurrently have at most an insignificant adverse affect on pharmacological activity.