84040-29-9

Basic information

• Product Name: 2-bromo-2-cyclopropyl-1-phenylethan-1-one
• Synonyms: 2-bromo-2-cyclopropyl-1-phenylethan-1-one
• CAS NO: 84040-29-9
• Molecular Weight: 239.112
• Mol File: 84040-29-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-bromo-2-cyclopropyl-1-phenylethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-2-cyclopropyl-1-phenylethan-1-one(84040-29-9)
• EPA Substance Registry System: 2-bromo-2-cyclopropyl-1-phenylethan-1-one(84040-29-9)

Safety Data

• Hazardous Substances Data: 84040-29-9(Hazardous Substances Data)

Upstream product

• 6542-60-5 2-cyclopropylacetonitrile 
• 100-58-3 phenylmagnesium bromide 
• 14113-94-1 2-phenyl-1-cyclopropylethan-1-one 
• 6739-22-6 2-cyclopropyl-1-phenylethanone 

Downstream Products

• 6739-22-6 2-cyclopropyl-1-phenylethanone 
• 3240-29-7 1-Phenylpent-4-en-1-one 

Relevant articles and documents

Acridine Orange Hemi(Zinc Chloride) Salt as a Lewis Acid-Photoredox Hybrid Catalyst for the Generation of α-Carbonyl Radicals

A readily accessible organic-inorganic hybrid catalyst is reported for the reductive fragmentation of α-halocarbonyl compounds. The robust hybrid catalyst is a self-stabilizing combination of ZnCl2 Lewis acid and acridine orange as the photoactive organic dye. Mechanistic specifics of this hybrid catalyst have been studied in detail using both photophysical and electrochemical experiments. A systematic study enabled the discovery of the appropriate Lewis acid for the effective LUMO stabilization of α-halocarbonyl compounds and thereby lowering of reduction potential within the range of a standard organic dye. This strategy resolves the issues like dehalogenative hydrogenation or homo-coupling of alkyl radicals by guiding the photoredox cycle through an oxidative quenching pathway. The cooperativity between the photoactive organic dye and the Lewis acid counterparts empowers functionalization with a wide range of coupling partners through efficient and controlled generation of alkyl radicals and serves as an appropriate alternative to the expensive late transition metal-based photocatalysts. To demonstrate the application potential of this cooperative catalytic system, four different synthetic transformations of α-carbonyl bromides were explored with broad substrate scopes.

Prasugrel defluorinated impurity compound, and preparation method and application thereof

The invention discloses a prasugrel defluorinated impurity compound as shown in a formula (I) which is described in the specification, and a preparation method and application of a defluorinated impurity. Moreover, the invention provides application of the prasugrel defluorinated impurity as a standard reference substance. As the prasugrel defluorinated impurity is applied as a standard reference substance, the product quality of prasugrel can be improved.