841205-62-7Relevant articles and documents
Oxidative Alkoxycarbonylation of Alkynes by Means of Aryl α-Diimine Palladium(II) Complexes as Catalysts
Beltrani, Michela,Carfagna, Carla,Milani, Barbara,Mancuso, Raffaella,Gabriele, Bartolo,Fini, Francesco
, p. 3244 - 3253 (2016/10/21)
The straightforward in situ synthesized bis(2,6-diisopropyl)acenaphthenequinonediimine palladium triflate catalyst was generally employed for both the mono-alkoxycarbonylation of terminal alkynes, and the bis-alkoxycarbonylation of 1,2-disubstituted alkynes by using mild reaction conditions [carbon monoxide pressure (PCO)=4 bar, temperature=20 °C]. Utilizing low catalyst loading (down to 0.5 mol%), a variety of propiolic esters were synthesized with good to excellent isolated yields. Most importantly the system was very efficient not only with methanol but also with a range of different alcohols, starting from the less hindered benzyl alcohol to the most hindered ones, such as isopropyl alcohol and tert-butyl alcohol. In addition, aromatic and aliphatic 1,2-disubstituted alkynes were converted into maleic acid derivatives, together with an acid-catalyzed isomerization reaction, showing modest to good selectivity and excellent combined yields. In particular 3-hexyne showed a satisfactory degree of selectivity for the maleic diesters of methanol and benzyl alcohol, obtaining the corresponding products with good isolated yields. (Figure presented.).
Synthesis of sterically hindered biaryls by Zr-mediated Co-cyclotrimerization of alkynes
Dufkova, Lenka,Kotora, Martin,Cisarova, Ivana
, p. 2491 - 2499 (2007/10/03)
Treatment of zirconacyclopentadienes with ortho-substituted arylpropynoates in the presence of stoichiometric amounts of CuCl or NiBr 2(PPh3)2 represents a novel approach to the synthesis of biaryls, formed in good yields. The CuCl-mediated reaction proceeded through two reaction mechanisms, also affording Dewar benzenes together with the corresponding biaryls Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005.
