841222-62-6 Usage
Description
4-METHYL-4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID is an organic compound with a unique chemical structure that features a thieno[3,2-b]pyrrole core and a carboxylic acid functional group. 4-METHYL-4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID has potential applications in various fields, particularly in the pharmaceutical industry, due to its ability to act as a lysine-specific demethylase-1 (LSD1) inhibitor.
Uses
Used in Pharmaceutical Industry:
4-METHYL-4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID is used as a lysine-specific demethylase-1 (LSD1) inhibitor for the treatment of cancer. LSD1 is an enzyme involved in the regulation of gene expression, and its overexpression has been associated with various types of cancer. By inhibiting LSD1, this compound can potentially disrupt cancer cell growth and proliferation, making it a promising candidate for cancer therapy.
In the development of novel therapeutic agents, 4-METHYL-4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID can be further optimized and modified to improve its potency, selectivity, and pharmacokinetic properties. This may lead to the discovery of new and more effective drugs for the treatment of various types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 841222-62-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,1,2,2 and 2 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 841222-62:
(8*8)+(7*4)+(6*1)+(5*2)+(4*2)+(3*2)+(2*6)+(1*2)=136
136 % 10 = 6
So 841222-62-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H7NO2S/c1-9-5-2-3-12-7(5)4-6(9)8(10)11/h2-4H,1H3,(H,10,11)
841222-62-6Relevant articles and documents
Synthesis of N-Substituted Methyl 4H-Thieno[3,2-b]pyrrole-5-carboxylates
Torosyan,Gimalova,Zagitov,Erastov,Miftakhov
, p. 912 - 917 (2018)
The alkylation of methyl 4H-thieno[3,2-b]pyrrole-5-carboxylate with methyl iodide and allyl, propargyl, and benzyl bromides in the presence of sodium hydride in THF afforded the corresponding N-substituted derivatives. Some reactions of the alkylation products were studied.
