84174-33-4

Basic information

• Product Name: 2-(2-methoxyphenyl)-2-phenylethanol
• Synonyms: 2-(2-methoxyphenyl)-2-phenylethanol
• CAS NO: 84174-33-4
• Molecular Weight: 228.291
• Mol File: 84174-33-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-(2-methoxyphenyl)-2-phenylethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-methoxyphenyl)-2-phenylethanol(84174-33-4)
• EPA Substance Registry System: 2-(2-methoxyphenyl)-2-phenylethanol(84174-33-4)

Safety Data

• Hazardous Substances Data: 84174-33-4(Hazardous Substances Data)

Upstream product

• 20780-53-4 (R)-Styrene oxide 
• 100-66-3 methoxybenzene 
• 96-09-3 styrene oxide 
• 920-66-1 1,1,1,3',3',3'-hexafluoro-propanol 
• 60-29-7 diethyl ether 
• 63059-15-4 (2-methoxy-phenyl)-phenyl-acetaldehyde 
• 67-56-1 methanol 
• 83922-77-4 2-methoxyphenyl(phenyl)diazomethane 

Downstream Products

• 55962-04-4 2-phenyl-2,3-dihydrobenzofuran 

Relevant articles and documents

Tetraphenylphosphonium Tetrafluoroborate/1,1,1,3,3,3-Hexafluoroisopropanol (Ph4PBF4/HFIP) Effecting Epoxide-Initiated Cation-Olefin Polycyclizations

The use of an excess amount of tetraphenylphosphonium tetrafluoroborate in 1,1,1,3,3,3-hexafluoroisopropanol, which can stabilize the intermediate cation in the reaction, efficiently promoted epoxide-initiated cation-olefin polycyclization reactions with broad functional group tolerance and water and oxygen tolerance.

1,2-Diarylethanols by alternative regioselective reductive ring-opening of 2,3-diaryloxiranes

Non-symmetrical ￡rans-2,3-diaryloxiranes have been regioselectively opened by catalytic hydrogenation over Pd/C, NaBH4/Pd and [Cp 2TiCl]/H2O. Although in the catalytic hydrogenation reactions the epoxides were mainly opened at the β-carbon with respect to the substituted aryl ring in all cases, with the [Cp2TiCl]/H 2O system the regioselectivity was affected by the electronic properties of the aryl residues, the epoxides being opened on the carbon bearing the most electron-releasing or the least electron-withdrawing group. With the NaBH4/Pd system different regioisomers were obtained depending on the substituents. Starting from enantioenriched epoxides, no loss of optical purity was observed in the alcohols formed.

Generation and Reactions of 2-Alkoxydiphenylcarbenes in Fluid Solution and Rigid Matrices

Irradiation of 2-alkoxydiphenyldiazomethanes 1 in cyclohexane at room temperature produced 3-phenyldihydrobenzofurans 3 presumably as a result of intramolecular C-H insertion of 2-alkoxydiphenylcarbenes 2.Irradiation of compounds 1 in cyclohexane matrix at -196 deg C gave intermolecular C-H insertion products 4 at the expense of benzofurans 3.The formation of products 4 is explicable in terms of H-atom tunnelling to the triplet state of carbenes 2, followed by coupling of the resulting radical pairs.Product ratios 3:4 were somewhat sensitive to the bulk of the alkoxy group at the 2-position.This can be explained in terms of the matrix effect on the relative population of the rotational isomers of the carbene 2.Irradiation of compounds 1 in methanol at room temperature afforded O-H insertion products 5 almost exclusively, whereas irradiation in methanol matrix at -196 deg C gave C-H insertion products 6 along with other products 3 and 5.