84194-91-2 Usage
Description
(1R,2S)-2-CHLORO-1,2,3,4-TETRAHYDRO-NAPHTHALEN-1-OL is a chiral alcohol featuring a chlorine atom attached to the second carbon and a hydroxyl group on the first carbon of a tetrahydronaphthalene ring. (1R,2S)-2-CHLORO-1,2,3,4-TETRAHYDRO-NAPHTHALEN-1-OL is significant in the field of organic synthesis and medicinal chemistry due to its unique stereochemistry, which influences its reactivity and selectivity in chemical reactions.
Uses
Used in Organic Synthesis:
(1R,2S)-2-CHLORO-1,2,3,4-TETRAHYDRO-NAPHTHALEN-1-OL is used as a building block in organic synthesis for the creation of more complex molecules. Its unique structure allows for the development of a variety of chemical entities with potential applications across different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (1R,2S)-2-CHLORO-1,2,3,4-TETRAHYDRO-NAPHTHALEN-1-OL is utilized as a starting material for the synthesis of various drugs and biologically active compounds. Its stereochemistry plays a crucial role in determining the efficacy and selectivity of the resulting pharmaceuticals, making it a valuable component in drug discovery and development processes.
Check Digit Verification of cas no
The CAS Registry Mumber 84194-91-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,1,9 and 4 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 84194-91:
(7*8)+(6*4)+(5*1)+(4*9)+(3*4)+(2*9)+(1*1)=152
152 % 10 = 2
So 84194-91-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H11ClO/c11-9-6-5-7-3-1-2-4-8(7)10(9)12/h1-4,9-10,12H,5-6H2/t9-,10+/m0/s1
84194-91-2Relevant articles and documents
Cross-Linked Artificial Enzyme Crystals as Heterogeneous Catalysts for Oxidation Reactions
Lopez, Sarah,Rondot, Laurianne,Leprêtre, Chloé,Marchi-Delapierre, Caroline,Ménage, Stéphane,Cavazza, Christine
supporting information, p. 17994 - 18002 (2017/12/26)
Designing systems that merge the advantages of heterogeneous catalysis, enzymology, and molecular catalysis represents the next major goal for sustainable chemistry. Cross-linked enzyme crystals display most of these essential assets (well-designed mesoporous support, protein selectivity, and molecular recognition of substrates). Nevertheless, a lack of reaction diversity, particularly in the field of oxidation, remains a constraint for their increased use in the field. Here, thanks to the design of cross-linked artificial nonheme iron oxygenase crystals, we filled this gap by developing biobased heterogeneous catalysts capable of oxidizing carbon-carbon double bonds. First, reductive O2 activation induces selective oxidative cleavage, revealing the indestructible character of the solid catalyst (at least 30 000 turnover numbers without any loss of activity). Second, the use of 2-electron oxidants allows selective and high-efficiency hydroxychlorination with thousands of turnover numbers. This new technology by far outperforms catalysis using the inorganic complexes alone, or even the artificial enzymes in solution. The combination of easy catalyst synthesis, the improvement of "omic" technologies, and automation of protein crystallization makes this strategy a real opportunity for the future of (bio)catalysis.