84211-75-6

Basic information

• Product Name: [131I]p-iodoanisole
• Synonyms: [131I]p-iodoanisole
• CAS NO: 84211-75-6
• Molecular Weight: 238.132
• Mol File: 84211-75-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: [131I]p-iodoanisole(CAS DataBase Reference)
• NIST Chemistry Reference: [131I]p-iodoanisole(84211-75-6)
• EPA Substance Registry System: [131I]p-iodoanisole(84211-75-6)

Safety Data

• Hazardous Substances Data: 84211-75-6(Hazardous Substances Data)

Upstream product

• 5720-07-0 4-methoxyphenylboronic acid 
• 79-21-0 peracetic acid 
• 14476-81-4 (4-methoxyphenyl)trimethylgermane 
• 20461-54-5 [131I]iodide 
• 100-66-3 methoxybenzene 
• 877-68-9 4-trimethylsilylanisole 

Relevant articles and documents

A Highly Efficient Copper-Mediated Radioiodination Approach Using Aryl Boronic Acids

A convenient and quantitative radioiodination method by copper-mediated cross-coupling of aryl boronic acids was developed. The mild labeling conditions, ready availability of the boronic acid substrate, simple operation, broad functional group tolerance and excellent radiochemical yield (RCY) make this a practical strategy for radioiodine labeling without further purification.

N.c.a. radioiodination of deactivated arenes with N-chlorosuccinimide in trifluoromethanesulfonic acid

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No-carrier-added Radiobromination and Radioiodination of Aromatic Rings using In Situ Generated Peracetic Acid

Peracetic acid generated in situ from aqueous hydrogen peroxide and glacial acetic acid was examined as an oxidizing agent for electrophilic aromatic bromination and iodination without chlorinated side products.No-carrier-added (n.c.a.) 77Br and 131I were used with simple organic aromatic compounds or aryltrimethyl-tin, -germanium, and -silicon organometallic compounds to identify reaction parameters which influence this electrophilic halogenation method.N.c.a. aromatic halogenodeprotonation using peracetic acid was relatively slow and resulted in high labelling yields only with aromatic rings that were activated toward electrophilic substitution.By contrast, high radiochemical yields were rapidly obtained via iododestannylation of aromatic rings regardless of their degree of electronic activation.Useful labelling yields were also achieved using bromodestannylation reactions with aromatic rings deactivated toward electrophiles, but optimum yields with activated systems required the use of germylated arenes as substrates.The practical aspects of aromatic halogenodemetallation and halogenodeprotonation as n.c.a. electrophilic halogenation techniques with in situ generated peracetic acid are outlined.