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842136-58-7

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842136-58-7 Usage

General Description

6-FLUOROPYRIDINE-2-BORONIC ACID PINACOL ESTER is a chemical compound with the formula C11H14BFNO3. It is a boronic acid derivative, specifically a pinacol ester, which is commonly used in organic synthesis and pharmaceutical research as a versatile building block for the development of novel drugs and organic compounds. 6-FLUOROPYRIDINE-2-BORONIC ACID PINACOL ESTER is known for its stability and reactivity, making it a valuable tool for the formation of carbon-carbon and carbon-heteroatom bonds. Its fluoropyridine group also imparts unique properties that can be exploited in the design of bioactive molecules. Overall, 6-FLUOROPYRIDINE-2-BORONIC ACID PINACOL ESTER is a valuable chemical for the advancement of medicinal and organic chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 842136-58-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,2,1,3 and 6 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 842136-58:
(8*8)+(7*4)+(6*2)+(5*1)+(4*3)+(3*6)+(2*5)+(1*8)=157
157 % 10 = 7
So 842136-58-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H15BFNO2/c1-10(2)11(3,4)16-12(15-10)8-6-5-7-9(13)14-8/h5-7H,1-4H3

842136-58-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

1.2 Other means of identification

Product number -
Other names 2-fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:842136-58-7 SDS

842136-58-7Relevant articles and documents

The discovery of novel 3-aryl-indazole derivatives as peripherally restricted pan-Trk inhibitors for the treatment of pain

Shirahashi, Hiromitsu,Toriihara, Eisuke,Suenaga, Yoshihito,Yoshida, Hideyuki,Akaogi, Kensuke,Endou, Yukiko,Wakabayashi, Makoto,Takashima, Misato

supporting information, p. 2320 - 2326 (2019/06/25)

The design, synthesis, and biological evaluation of novel 3-aryl-indazole derivatives as peripherally selective pan-Trk inhibitors are described. Three strategies were used to obtain a potent compound exhibiting low central nervous system (CNS) penetratio

PYRROLO[2,3-B]PYRIDINE CDK9 KINASE INHIBITORS

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Page/Page column 403, (2014/09/29)

Disclosed are compounds of Formula (IIa), wherein R1, R2, R3A, R3B, R3C, R3D, R3E, and R4 are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds may be used as agents in the treatment of diseases, including cancer. Also provided are pharmaceutical compositions comprising one or more compounds of Formula (IIa)

N-ACYL PYRIMIDINE BIARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS

-

Page/Page column 185, (2012/08/08)

The present invention provides a compound of the general formula (1): wherein one of X and Y is N and the other is an optionally substituted carbon atom, and Z2-Z5 represent one or two nitrogen atoms, as further described herein, including pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. These compounds inhibit the activity of CDK9 and are thus useful as pharmaceuticals and as components of pharmaceutical compositions. Also provided are methods of treating a disease or condition mediated by CDK9 using the compounds described herein or pharmaceutical compositions comprising such compounds.

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