842162-99-6 Usage
Description
4-tert-ButyldiMethylsilyl Atorvastatin Lactone is a chemical derivative of Atorvastatin Lactone (A791780), which is a key intermediate in the synthesis of atorvastatin, a widely used cholesterol-lowering drug.
Used in Pharmaceutical Industry:
4-tert-ButyldiMethylsilyl Atorvastatin Lactone is used as a chemical intermediate for the preparation of N-substituted pyrrole derivatives, which are crucial in the synthesis of atorvastatin. This application is significant in the development and production of cholesterol-lowering medications, contributing to the treatment and management of cardiovascular diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 842162-99-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,2,1,6 and 2 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 842162-99:
(8*8)+(7*4)+(6*2)+(5*1)+(4*6)+(3*2)+(2*9)+(1*9)=166
166 % 10 = 6
So 842162-99-6 is a valid CAS Registry Number.
842162-99-6Relevant articles and documents
Process for preparing C7 intermediates and their use in the preparation on N-substituted pyrrole derivatives
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Page/Page column 29-30, (2010/11/28)
The present invention relates to a process for preparing C7 intermediates and their use in the preparation of pyrrole derivatives of a class that is effective at inhibiting the biosynthesis of cholesterol in humans, and more particularly to improved synthetic methods for preparing 3,5-dihydroxy-7-pyrrol-1-yl heptanoic acids. The invention further relates to intermediates in this process.